rs9545925

Homo sapiens
G>T
DCLK1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0456 (13657/29906,GnomAD)
T=0404 (11790/29116,TOPMED)
T=0422 (2111/5008,1000G)
G==0455 (1752/3854,ALSPAC)
G==0432 (1602/3708,TWINSUK)
chr13:35961055 (GRCh38.p7) (13q13.3)
AD
GWASdb2
1   publication(s)
See rs on genome
189 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 13NC_000013.11:g.35961055G>T
GRCh37.p13 chr 13NC_000013.10:g.36535192G>T

Gene: DCLK1, doublecortin like kinase 1(minus strand)

Molecule type Change Amino acid[Codon] SO Term
DCLK1 transcript variant 1NM_004734.4:c.N/AIntron Variant
DCLK1 transcript variant 2NM_001195415.1:c.N/AGenic Upstream Transcript Variant
DCLK1 transcript variant 3NM_001195416.1:c.N/AGenic Upstream Transcript Variant
DCLK1 transcript variant 4NM_001195430.1:c.N/AGenic Upstream Transcript Variant
DCLK1 transcript variant X1XM_005266592.2:c.N/AIntron Variant
DCLK1 transcript variant X2XM_006719893.2:c.N/AIntron Variant
DCLK1 transcript variant X1XM_017020847.1:c.N/AIntron Variant
DCLK1 transcript variant X2XM_017020848.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.815T=0.185
1000GenomesAmericanSub694G=0.420T=0.580
1000GenomesEast AsianSub1008G=0.599T=0.401
1000GenomesEuropeSub1006G=0.453T=0.547
1000GenomesGlobalStudy-wide5008G=0.578T=0.422
1000GenomesSouth AsianSub978G=0.480T=0.520
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.455T=0.545
The Genome Aggregation DatabaseAfricanSub8698G=0.769T=0.231
The Genome Aggregation DatabaseAmericanSub828G=0.450T=0.550
The Genome Aggregation DatabaseEast AsianSub1606G=0.589T=0.411
The Genome Aggregation DatabaseEuropeSub18472G=0.436T=0.563
The Genome Aggregation DatabaseGlobalStudy-wide29906G=0.543T=0.456
The Genome Aggregation DatabaseOtherSub302G=0.570T=0.430
Trans-Omics for Precision MedicineGlobalStudy-wide29116G=0.595T=0.404
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.432T=0.568
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs95459250.000343alcohol dependence20201924

eQTL of rs9545925 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs9545925 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr133649129336491476E067-43716
chr133649153236491766E067-43426
chr133649181936491954E067-43238
chr133649195536492278E067-42914
chr133649240036492460E067-42732
chr133649251136492706E067-42486
chr133652757336528789E067-6403
chr133653209536532166E067-3026
chr133653228436532391E067-2801
chr133655266536554298E06717473
chr133655836536558445E06723173
chr133655856536558749E06723373
chr133655891336559494E06723721
chr133649101736491257E068-43935
chr133649129336491476E068-43716
chr133650106336501236E068-33956
chr133650138736501648E068-33544
chr133655836536558445E06823173
chr133655856536558749E06823373
chr133655891336559494E06823721
chr133655964836559917E06824456
chr133656208736562697E06826895
chr133656273136563315E06827539
chr133652757336528789E069-6403
chr133655266536554298E06917473
chr133655856536558749E06923373
chr133655891336559494E06923721
chr133655964836559917E06924456
chr133656674736566897E06931555
chr133656718636567308E06931994
chr133656737436567583E06932182
chr133657404536574195E06938853
chr133652674636526863E070-8329
chr133652690236527131E070-8061
chr133652723336527291E070-7901
chr133652757336528789E070-6403
chr133652940336529507E070-5685
chr133655828136558351E07023089
chr133655836536558445E07023173
chr133655856536558749E07023373
chr133655891336559494E07023721
chr133655964836559917E07024456
chr133656079036560897E07025598
chr133656089836561018E07025706
chr133656121036561300E07026018
chr133656164536561993E07026453
chr133656208736562697E07026895
chr133656273136563315E07027539
chr133656331836563466E07028126
chr133656674736566897E07031555
chr133656718636567308E07031994
chr133656737436567583E07032182
chr133656826336569178E07033071
chr133656918036569237E07033988
chr133652757336528789E071-6403
chr133655266536554298E07117473
chr133655891336559494E07123721
chr133655964836559917E07124456
chr133655266536554298E07217473
chr133655891336559494E07223721
chr133655964836559917E07224456
chr133656636236566424E07231170
chr133656669636566746E07231504
chr133656674736566897E07231555
chr133656718636567308E07231994
chr133656737436567583E07232182
chr133656769636567818E07232504
chr133649101736491257E073-43935
chr133649129336491476E073-43716
chr133649153236491766E073-43426
chr133649181936491954E073-43238
chr133649195536492278E073-42914
chr133653069936530795E073-4397
chr133655011136550198E07314919
chr133655032336550596E07315131
chr133655266536554298E07417473
chr133655891336559494E07423721
chr133649089736490972E081-44220
chr133651875636518834E081-16358
chr133651941036520075E081-15117
chr133652054036520599E081-14593
chr133652098036521112E081-14080
chr133652723336527291E081-7901
chr133652757336528789E081-6403
chr133652880536528881E081-6311
chr133652916136529280E081-5912
chr133652940336529507E081-5685
chr133652962136529677E081-5515
chr133652969936529795E081-5397
chr133652987436530024E081-5168
chr133653008836530166E081-5026
chr133653022436530378E081-4814
chr133653069936530795E081-4397
chr133653209536532166E081-3026
chr133653228436532391E081-2801
chr133653269736532747E081-2445
chr133653277136532825E081-2367
chr133653287636533003E081-2189
chr133653315436533198E081-1994
chr133653525836535388E08166
chr133653546036535574E081268
chr133653575936536116E081567
chr133653613036536214E081938
chr133653639936536597E0811207
chr133653674736537085E0811555
chr133653710136537296E0811909
chr133653733336537424E0812141
chr133653748536537535E0812293
chr133653773136537841E0812539
chr133653790336537983E0812711
chr133655011136550198E08114919
chr133655032336550596E08115131
chr133655074236550792E08115550
chr133655101536551141E08115823
chr133655124436551549E08116052
chr133655188636551962E08116694
chr133655205336552120E08116861
chr133655218136552284E08116989
chr133655239436552465E08117202
chr133655266536554298E08117473
chr133655828136558351E08123089
chr133655836536558445E08123173
chr133655856536558749E08123373
chr133655891336559494E08123721
chr133655964836559917E08124456
chr133656047436560557E08125282
chr133656079036560897E08125598
chr133656089836561018E08125706
chr133656121036561300E08126018
chr133656164536561993E08126453
chr133656208736562697E08126895
chr133656273136563315E08127539
chr133656331836563466E08128126
chr133656737436567583E08132182
chr133656769636567818E08132504
chr133656793436568035E08132742
chr133656804036568095E08132848
chr133656826336569178E08133071
chr133656918036569237E08133988
chr133656980736569898E08134615
chr133656990236569981E08134710
chr133657037536570463E08135183
chr133658036236580966E08145170
chr133658105736581833E08145865
chr133649021136490624E082-44568
chr133649089736490972E082-44220
chr133651941036520075E082-15117
chr133652054036520599E082-14593
chr133652653536526641E082-8551
chr133652674636526863E082-8329
chr133652690236527131E082-8061
chr133652723336527291E082-7901
chr133652880536528881E082-6311
chr133652916136529280E082-5912
chr133652940336529507E082-5685
chr133652962136529677E082-5515
chr133652969936529795E082-5397
chr133652987436530024E082-5168
chr133653008836530166E082-5026
chr133653022436530378E082-4814
chr133653506536535149E082-43
chr133653525836535388E08266
chr133653546036535574E082268
chr133653575936536116E082567
chr133653613036536214E082938
chr133653639936536597E0821207
chr133653674736537085E0821555
chr133653710136537296E0821909
chr133653733336537424E0822141
chr133653748536537535E0822293
chr133655101536551141E08215823
chr133655124436551549E08216052
chr133655836536558445E08223173
chr133655856536558749E08223373
chr133655964836559917E08224456
chr133656208736562697E08226895
chr133656273136563315E08227539
chr133656331836563466E08228126
chr133656636236566424E08231170
chr133656669636566746E08231504
chr133656674736566897E08231555
chr133656718636567308E08231994
chr133656737436567583E08232182
chr133656769636567818E08232504
chr133656793436568035E08232742
chr133656804036568095E08232848
chr133656826336569178E08233071
chr133656918036569237E08233988
chr133657063836570764E08235446