SNP Detail Info-rs9576027

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0295 (8613/29118,TOPMED)
G=0349 (10170/29100,GnomAD)
G=0481 (2411/5008,1000G)
G=0355 (1368/3854,ALSPAC)
G=0333 (1234/3708,TWINSUK)

Position: chr13:86154873 (GRCh38.p7) (13q31.1)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 13	NC_000013.11:g.86154873A>G
GRCh37.p13 chr 13	NC_000013.10:g.86729008A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.859	G=0.141
1000Genomes	American	Sub	694	A=0.480	G=0.520
1000Genomes	East Asian	Sub	1008	A=0.062	G=0.938
1000Genomes	Europe	Sub	1006	A=0.617	G=0.383
1000Genomes	Global	Study-wide	5008	A=0.519	G=0.481
1000Genomes	South Asian	Sub	978	A=0.460	G=0.540
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.645	G=0.355
The Genome Aggregation Database	African	Sub	8628	A=0.823	G=0.177
The Genome Aggregation Database	American	Sub	724	A=0.440	G=0.560
The Genome Aggregation Database	East Asian	Sub	1622	A=0.080	G=0.920
The Genome Aggregation Database	Europe	Sub	17824	A=0.626	G=0.373
The Genome Aggregation Database	Global	Study-wide	29100	A=0.650	G=0.349
The Genome Aggregation Database	Other	Sub	302	A=0.680	G=0.320
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.704	G=0.295
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.667	G=0.333

PMID	Title	Author	Journal
24277619	ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.	Quillen EE	Am J Med Genet B Neuropsychiatr Genet

SNP ID	p-value	Traits	Study
rs9576027	0.000328	alcohol dependence	24277619

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs9576027