SNP Detail Info-rs9587583

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0090 (2707/29958,GnomAD)
A=0097 (2851/29118,TOPMED)
A=0087 (438/5008,1000G)
A=0086 (330/3854,ALSPAC)
A=0082 (304/3708,TWINSUK)

Position: chr13:108437268 (GRCh38.p7) (13q33.3)

Phenotype: AD

Dataset:

GWASdb2

Publications: 2 publication(s)

Genomic View: See rs on genome

Enhancer: 8 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 13	NC_000013.11:g.108437268G>A
GRCh37.p13 chr 13	NC_000013.10:g.109089616G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.890	A=0.110
1000Genomes	American	Sub	694	G=0.940	A=0.060
1000Genomes	East Asian	Sub	1008	G=0.894	A=0.106
1000Genomes	Europe	Sub	1006	G=0.918	A=0.082
1000Genomes	Global	Study-wide	5008	G=0.913	A=0.087
1000Genomes	South Asian	Sub	978	G=0.940	A=0.060
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.914	A=0.086
The Genome Aggregation Database	African	Sub	8728	G=0.893	A=0.107
The Genome Aggregation Database	American	Sub	836	G=0.940	A=0.060
The Genome Aggregation Database	East Asian	Sub	1612	G=0.917	A=0.083
The Genome Aggregation Database	Europe	Sub	18480	G=0.915	A=0.084
The Genome Aggregation Database	Global	Study-wide	29958	G=0.909	A=0.090
The Genome Aggregation Database	Other	Sub	302	G=0.910	A=0.090
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.902	A=0.097
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.918	A=0.082

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res
21628991	Genome-wide scan of granular corneal dystrophy, type II: confirmation of chromosome 5q31 and identification of new co-segregated loci on chromosome 3q26.3.	Lee EJ	Exp Mol Med

SNP ID	p-value	Traits	Study
rs9587583	0.000917	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr13	109055425	109056007	E069	-33609
chr13	109061181	109061329	E070	-28287
chr13	109061343	109061531	E070	-28085
chr13	109061579	109061693	E070	-27923
chr13	109055425	109056007	E081	-33609
chr13	109110886	109110951	E081	21270
chr13	109113040	109113386	E081	23424
chr13	109115558	109116369	E081	25942

rs9587583