rs9587583

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0090 (2707/29958,GnomAD)
A=0097 (2851/29118,TOPMED)
A=0087 (438/5008,1000G)
A=0086 (330/3854,ALSPAC)
A=0082 (304/3708,TWINSUK)
chr13:108437268 (GRCh38.p7) (13q33.3)
AD
GWASdb2
2   publication(s)
See rs on genome
8 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 13NC_000013.11:g.108437268G>A
GRCh37.p13 chr 13NC_000013.10:g.109089616G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.890A=0.110
1000GenomesAmericanSub694G=0.940A=0.060
1000GenomesEast AsianSub1008G=0.894A=0.106
1000GenomesEuropeSub1006G=0.918A=0.082
1000GenomesGlobalStudy-wide5008G=0.913A=0.087
1000GenomesSouth AsianSub978G=0.940A=0.060
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.914A=0.086
The Genome Aggregation DatabaseAfricanSub8728G=0.893A=0.107
The Genome Aggregation DatabaseAmericanSub836G=0.940A=0.060
The Genome Aggregation DatabaseEast AsianSub1612G=0.917A=0.083
The Genome Aggregation DatabaseEuropeSub18480G=0.915A=0.084
The Genome Aggregation DatabaseGlobalStudy-wide29958G=0.909A=0.090
The Genome Aggregation DatabaseOtherSub302G=0.910A=0.090
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.902A=0.097
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.918A=0.082
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res
21628991Genome-wide scan of granular corneal dystrophy, type II: confirmation of chromosome 5q31 and identification of new co-segregated loci on chromosome 3q26.3.Lee EJExp Mol Med

P-Value

SNP ID p-value Traits Study
rs95875830.000917alcohol dependence20201924

eQTL of rs9587583 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs9587583 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr13109055425109056007E069-33609
chr13109061181109061329E070-28287
chr13109061343109061531E070-28085
chr13109061579109061693E070-27923
chr13109055425109056007E081-33609
chr13109110886109110951E08121270
chr13109113040109113386E08123424
chr13109115558109116369E08125942