rs9595835

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0295 (8856/29948,GnomAD)
C=0345 (10054/29116,TOPMED)
C=0336 (1685/5008,1000G)
C=0194 (748/3854,ALSPAC)
C=0201 (746/3708,TWINSUK)
chr13:48054313 (GRCh38.p7) (13q14.2)
AD
GWASdb2
1   publication(s)
See rs on genome
28 Enhancers around
20 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 13NC_000013.11:g.48054313T>C
GRCh37.p13 chr 13NC_000013.10:g.48628449T>C
NUDT15 RefSeqGeneNG_047021.1:g.21747T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.405C=0.595
1000GenomesAmericanSub694T=0.720C=0.280
1000GenomesEast AsianSub1008T=0.687C=0.313
1000GenomesEuropeSub1006T=0.812C=0.188
1000GenomesGlobalStudy-wide5008T=0.664C=0.336
1000GenomesSouth AsianSub978T=0.800C=0.200
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.806C=0.194
The Genome Aggregation DatabaseAfricanSub8704T=0.486C=0.514
The Genome Aggregation DatabaseAmericanSub838T=0.740C=0.260
The Genome Aggregation DatabaseEast AsianSub1614T=0.647C=0.353
The Genome Aggregation DatabaseEuropeSub18490T=0.808C=0.191
The Genome Aggregation DatabaseGlobalStudy-wide29948T=0.704C=0.295
The Genome Aggregation DatabaseOtherSub302T=0.810C=0.190
Trans-Omics for Precision MedicineGlobalStudy-wide29116T=0.654C=0.345
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.799C=0.201
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs95958350.000244alcohol dependence21314694

eQTL of rs9595835 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs9595835 in Fetal Brain

Probe ID Position Gene beta p-value
cg18221580chr13:48575897SUCLA2-0.09124573394665233.1904e-20
cg01732984chr13:48575859SUCLA2-0.05881226256556151.1099e-15

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr134866769648667766E06739247
chr134861263548613713E068-14736
chr134866701448667068E06838565
chr134866711248667250E06838663
chr134866732148667361E06838872
chr134866769648667766E06839247
chr134866701448667068E07238565
chr134866711248667250E07238663
chr134866732148667361E07238872
chr134866769648667766E07239247
chr134866682148666873E07338372
chr134866689548666981E07338446
chr134866701448667068E07338565
chr134866711248667250E07338663
chr134866732148667361E07338872
chr134866769648667766E07339247
chr134866769648667766E07439247
chr134866769648667766E08139247
chr134866551848665589E08237069
chr134866580848665858E08237359
chr134866609448666148E08237645
chr134866656648666669E08238117
chr134866673048666790E08238281
chr134866682148666873E08238372
chr134866689548666981E08238446
chr134866701448667068E08238565
chr134866711248667250E08238663
chr134866732148667361E08238872







Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr134861123748612634E067-15815
chr134866840048669625E06739951
chr134861123748612634E068-15815
chr134866840048669625E06839951
chr134861123748612634E069-15815
chr134866840048669625E06939951
chr134861123748612634E070-15815
chr134866840048669625E07039951
chr134861123748612634E071-15815
chr134866840048669625E07139951
chr134861123748612634E072-15815
chr134866840048669625E07239951
chr134861123748612634E073-15815
chr134866840048669625E07339951
chr134861123748612634E074-15815
chr134866840048669625E07439951
chr134861123748612634E081-15815
chr134866840048669625E08139951
chr134861123748612634E082-15815
chr134866840048669625E08239951