rs960740

Homo sapiens
T>A / T>G
None
Check p-value
SNV (Single Nucleotide Variation)
T==0493 (14455/29286,GnomAD)
T==0466 (13595/29118,TOPMED)
T==0488 (2442/5008,1000G)
A=0489 (1886/3854,ALSPAC)
A=0499 (1852/3708,TWINSUK)
chr4:35457552 (GRCh38.p7) (4p15.1)
ND
GWASdb2
1   publication(s)
See rs on genome
15 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.35457552T>A
GRCh38.p7 chr 4NC_000004.12:g.35457552T>G
GRCh37.p13 chr 4NC_000004.11:g.35459174T>A
GRCh37.p13 chr 4NC_000004.11:g.35459174T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.400A=0.600
1000GenomesAmericanSub694T=0.450A=0.550
1000GenomesEast AsianSub1008T=0.643A=0.357
1000GenomesEuropeSub1006T=0.538A=0.462
1000GenomesGlobalStudy-wide5008T=0.488A=0.512
1000GenomesSouth AsianSub978T=0.420A=0.580
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.511A=0.489
The Genome Aggregation DatabaseAfricanSub8584T=0.430G=0.000
The Genome Aggregation DatabaseAmericanSub822T=0.420G=0.00,
The Genome Aggregation DatabaseEast AsianSub1610T=0.674G=0.000
The Genome Aggregation DatabaseEuropeSub17970T=0.509G=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29286T=0.493G=0.000
The Genome Aggregation DatabaseOtherSub300T=0.580G=0.00,
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.466A=0.533
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.501A=0.499
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs9607400.000239nicotine dependence17158188

eQTL of rs960740 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs960740 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr44045148140451531E07038383
chr44045337840453587E07040280
chr44045369540453888E07040597
chr44039640940396556E074-16542
chr44039036940390544E081-22554
chr44045337840453587E08140280
chr44045369540453888E08140597
chr44045422440454506E08141126
chr44045455340454679E08141455
chr44045526340455313E08142165
chr44045533340455727E08142235
chr44044634040446412E08233242
chr44044646340446602E08233365
chr44045455340454679E08241455
chr44045526340455313E08242165