rs964744

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0235 (7042/29946,GnomAD)
C==0225 (6578/29118,TOPMED)
C==0195 (977/5008,1000G)
C==0234 (903/3854,ALSPAC)
C==0222 (822/3708,TWINSUK)
chr2:186017422 (GRCh38.p7) (2q32.1)
AD
GWASdb2
1   publication(s)
See rs on genome
25 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.186017422C>T
GRCh37.p13 chr 2NC_000002.11:g.186882149C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.256T=0.744
1000GenomesAmericanSub694C=0.160T=0.840
1000GenomesEast AsianSub1008C=0.064T=0.936
1000GenomesEuropeSub1006C=0.214T=0.786
1000GenomesGlobalStudy-wide5008C=0.195T=0.805
1000GenomesSouth AsianSub978C=0.250T=0.750
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.234T=0.766
The Genome Aggregation DatabaseAfricanSub8718C=0.275T=0.725
The Genome Aggregation DatabaseAmericanSub838C=0.130T=0.870
The Genome Aggregation DatabaseEast AsianSub1610C=0.075T=0.925
The Genome Aggregation DatabaseEuropeSub18478C=0.235T=0.764
The Genome Aggregation DatabaseGlobalStudy-wide29946C=0.235T=0.764
The Genome Aggregation DatabaseOtherSub302C=0.230T=0.770
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.225T=0.774
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.222T=0.778
PMID Title Author Journal
22072270Genome-wide association study identifies 5q21 and 9p24.1 (KDM4C) loci associated with alcohol withdrawal symptoms.Wang KSJ Neural Transm (Vienna)

P-Value

SNP ID p-value Traits Study
rs9647447.91E-05alcohol withdrawal symptoms22072270

eQTL of rs964744 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
Chr2:186882149RP11-410E4.1ENSG00000259915.1C>T2.2822e-6-339351Frontal_Cortex_BA9
Chr2:186882149RP11-410E4.1ENSG00000259915.1C>T1.2644e-5-339351Cortex
Chr2:186882149RP11-410E4.1ENSG00000259915.1C>T1.8646e-10-339351Putamen_basal_ganglia

meQTL of rs964744 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2186923483186923603E06741334
chr2186923871186924194E06741722
chr2186923483186923603E06841334
chr2186923871186924194E06841722
chr2186924218186924268E06842069
chr2186926402186926457E06844253
chr2186923483186923603E06941334
chr2186923483186923603E07041334
chr2186923871186924194E07041722
chr2186923483186923603E07141334
chr2186924218186924268E07142069
chr2186926402186926457E07144253
chr2186926651186926748E07144502
chr2186923483186923603E07241334
chr2186923871186924194E07241722
chr2186924218186924268E07242069
chr2186926402186926457E07244253
chr2186923483186923603E07341334
chr2186923871186924194E07341722
chr2186924218186924268E07442069
chr2186925550186925968E07443401
chr2186926402186926457E07444253
chr2186926651186926748E07444502
chr2186923483186923603E08241334
chr2186923871186924194E08241722