rs9661578

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0457 (13657/29848,GnomAD)
T=0450 (13108/29118,TOPMED)
C==0478 (2396/5008,1000G)
C==0353 (1362/3854,ALSPAC)
C==0359 (1331/3708,TWINSUK)
chr1:5821692 (GRCh38.p7) (1p36.31)
CD
GWASdb2
1   publication(s)
See rs on genome
18 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.5821692C>T
GRCh37.p13 chr 1NC_000001.10:g.5881752C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.865T=0.135
1000GenomesAmericanSub694C=0.330T=0.670
1000GenomesEast AsianSub1008C=0.148T=0.852
1000GenomesEuropeSub1006C=0.351T=0.649
1000GenomesGlobalStudy-wide5008C=0.478T=0.522
1000GenomesSouth AsianSub978C=0.530T=0.470
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.353T=0.647
The Genome Aggregation DatabaseAfricanSub8694C=0.792T=0.208
The Genome Aggregation DatabaseAmericanSub834C=0.330T=0.670
The Genome Aggregation DatabaseEast AsianSub1616C=0.124T=0.876
The Genome Aggregation DatabaseEuropeSub18404C=0.334T=0.665
The Genome Aggregation DatabaseGlobalStudy-wide29848C=0.457T=0.542
The Genome Aggregation DatabaseOtherSub300C=0.510T=0.490
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.549T=0.450
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.359T=0.641
PMID Title Author Journal
23958962Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene.Gelernter JMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs96615780.0000453cocaine dependence23958962
rs96615780.000061cocaine dependence,AA23958962

eQTL of rs9661578 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs9661578 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr159088985909016E06927146
chr158709325871043E070-10709
chr158710725871140E070-10612
chr158715325871720E070-10032
chr158719435871993E070-9759
chr159076765907839E07025924
chr159088985909016E07027146
chr159176835917857E07235931
chr159264805926717E07344728
chr158754795875547E074-6205
chr158999505900229E08118198
chr159007935900924E08119041
chr159088985909016E08127146
chr159095665909744E08127814
chr158999505900229E08218198
chr159007935900924E08219041
chr159042285904327E08222476
chr159088985909016E08227146