rs9661984

Homo sapiens
T>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0271 (8129/29922,GnomAD)
G=0237 (6914/29116,TOPMED)
G=0318 (1593/5008,1000G)
G=0286 (1103/3854,ALSPAC)
G=0280 (1037/3708,TWINSUK)
chr1:218909718 (GRCh38.p7) (1q41)
AD
GWASdb2
1   publication(s)
See rs on genome
6 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.218909718T>G
GRCh37.p13 chr 1NC_000001.10:g.219083060T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.841G=0.159
1000GenomesAmericanSub694T=0.730G=0.270
1000GenomesEast AsianSub1008T=0.485G=0.515
1000GenomesEuropeSub1006T=0.724G=0.276
1000GenomesGlobalStudy-wide5008T=0.682G=0.318
1000GenomesSouth AsianSub978T=0.590G=0.410
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.714G=0.286
The Genome Aggregation DatabaseAfricanSub8708T=0.814G=0.186
The Genome Aggregation DatabaseAmericanSub832T=0.770G=0.230
The Genome Aggregation DatabaseEast AsianSub1606T=0.480G=0.520
The Genome Aggregation DatabaseEuropeSub18474T=0.708G=0.291
The Genome Aggregation DatabaseGlobalStudy-wide29922T=0.728G=0.271
The Genome Aggregation DatabaseOtherSub302T=0.660G=0.340
Trans-Omics for Precision MedicineGlobalStudy-wide29116T=0.762G=0.237
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.720G=0.280
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs96619840.000742alcohol dependence24277619

eQTL of rs9661984 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs9661984 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1219060467219060770E068-22290
chr1219059922219060098E070-22962
chr1219060467219060770E070-22290
chr1219131386219131670E07148326
chr1219062277219062455E073-20605
chr1219062510219062637E073-20423