rs9676962

Homo sapiens
C>T
ZNF563 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0197 (5921/29926,GnomAD)
T=0200 (5850/29118,TOPMED)
T=0191 (958/5008,1000G)
T=0171 (658/3854,ALSPAC)
T=0160 (593/3708,TWINSUK)
chr19:12330430 (GRCh38.p7) (19p13.2)
AD
GWASdb2
1   publication(s)
See rs on genome
14 Enhancers around
29 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 19NC_000019.10:g.12330430C>T
GRCh37.p13 chr 19NC_000019.9:g.12441244C>T

Gene: ZNF563, zinc finger protein 563(minus strand)

Molecule type Change Amino acid[Codon] SO Term
ZNF563 transcript variant 1NM_145276.2:c.N/AIntron Variant
ZNF563 transcript variant X6XM_005259750.4:c.N/AIntron Variant
ZNF563 transcript variant X7XM_005259751.3:c.N/AIntron Variant
ZNF563 transcript variant X2XM_006722650.3:c.N/AIntron Variant
ZNF563 transcript variant X5XM_006722651.3:c.N/AIntron Variant
ZNF563 transcript variant X3XM_011527700.2:c.N/AIntron Variant
ZNF563 transcript variant X1XM_011527698.1:c.N/AGenic Upstream Transcript Variant
ZNF563 transcript variant X4XM_011527699.2:c.N/AGenic Upstream Transcript Variant
ZNF563 transcript variant X7XM_017026332.1:c.N/AGenic Upstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.773T=0.227
1000GenomesAmericanSub694C=0.840T=0.160
1000GenomesEast AsianSub1008C=0.766T=0.234
1000GenomesEuropeSub1006C=0.831T=0.169
1000GenomesGlobalStudy-wide5008C=0.809T=0.191
1000GenomesSouth AsianSub978C=0.860T=0.140
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.829T=0.171
The Genome Aggregation DatabaseAfricanSub8700C=0.775T=0.225
The Genome Aggregation DatabaseAmericanSub834C=0.860T=0.140
The Genome Aggregation DatabaseEast AsianSub1612C=0.721T=0.279
The Genome Aggregation DatabaseEuropeSub18478C=0.818T=0.181
The Genome Aggregation DatabaseGlobalStudy-wide29926C=0.802T=0.197
The Genome Aggregation DatabaseOtherSub302C=0.870T=0.130
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.799T=0.200
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.840T=0.160
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs96769620.000584alcohol dependence20201924

eQTL of rs9676962 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
Chr19:12441244PRKCSHENSG00000130175.5C>T6.3818e-8895135Cerebellum

meQTL of rs9676962 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr191247460812474657E06733364
chr191244515312445216E0683909
chr191240347112403514E070-37730
chr191240355012403635E070-37609
chr191244515312445216E0703909
chr191244515312445216E0713909
chr191244515312445216E0723909
chr191240335312403426E073-37818
chr191240347112403514E073-37730
chr191240355012403635E073-37609
chr191247419112474310E07332947
chr191247419112474310E07432947
chr191240347112403514E082-37730
chr191240355012403635E082-37609








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr191240434612406467E067-34777
chr191244335312445037E0672109
chr191247528812477355E06734044
chr191240434612406467E068-34777
chr191244335312445037E0682109
chr191247528812477355E06834044
chr191240434612406467E069-34777
chr191244335312445037E0692109
chr191247528812477355E06934044
chr191240434612406467E070-34777
chr191244335312445037E0702109
chr191247528812477355E07034044
chr191240434612406467E071-34777
chr191244335312445037E0712109
chr191247528812477355E07134044
chr191240434612406467E072-34777
chr191244335312445037E0722109
chr191247528812477355E07234044
chr191240434612406467E073-34777
chr191244335312445037E0732109
chr191247528812477355E07334044
chr191240434612406467E074-34777
chr191244335312445037E0742109
chr191247528812477355E07434044
chr191240434612406467E081-34777
chr191244335312445037E0812109
chr191240434612406467E082-34777
chr191244335312445037E0822109
chr191247528812477355E08234044