rs968433

Homo sapiens
C>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0338 (10128/29922,GnomAD)
G=0322 (9391/29118,TOPMED)
G=0326 (1634/5008,1000G)
G=0367 (1415/3854,ALSPAC)
G=0371 (1375/3708,TWINSUK)
chr20:4761434 (GRCh38.p7) (20p13)
AD
GWASdb2
1   publication(s)
See rs on genome
172 Enhancers around
21 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 20NC_000020.11:g.4761434C>G
GRCh37.p13 chr 20NC_000020.10:g.4742080C>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.724G=0.276
1000GenomesAmericanSub694C=0.590G=0.410
1000GenomesEast AsianSub1008C=0.689G=0.311
1000GenomesEuropeSub1006C=0.616G=0.384
1000GenomesGlobalStudy-wide5008C=0.674G=0.326
1000GenomesSouth AsianSub978C=0.710G=0.290
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.633G=0.367
The Genome Aggregation DatabaseAfricanSub8700C=0.722G=0.278
The Genome Aggregation DatabaseAmericanSub838C=0.580G=0.420
The Genome Aggregation DatabaseEast AsianSub1616C=0.705G=0.295
The Genome Aggregation DatabaseEuropeSub18468C=0.632G=0.367
The Genome Aggregation DatabaseGlobalStudy-wide29922C=0.661G=0.338
The Genome Aggregation DatabaseOtherSub300C=0.660G=0.340
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.677G=0.322
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.629G=0.371
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs9684330.000165alcohol dependence21314694

eQTL of rs968433 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs968433 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2046980324698104E067-43976
chr2046983014698410E067-43670
chr2046984684698521E067-43559
chr2046986024698669E067-43411
chr2046986894698847E067-43233
chr2047001614700224E067-41856
chr2047004624702017E067-40063
chr2047040604704100E067-37980
chr2047041814704254E067-37826
chr2047050934705233E067-36847
chr2047052574705345E067-36735
chr2047054114705485E067-36595
chr2047055954705812E067-36268
chr2047058964705953E067-36127
chr2047059644706098E067-35982
chr2047072324707344E067-34736
chr2047081574708319E067-33761
chr2047895734790051E06747493
chr2047902394790309E06748159
chr2047903244790841E06748244
chr2047908664791098E06748786
chr2047911744791533E06749094
chr2047915364791796E06749456
chr2046973584697408E068-44672
chr2046980324698104E068-43976
chr2046983014698410E068-43670
chr2046984684698521E068-43559
chr2046986024698669E068-43411
chr2046986894698847E068-43233
chr2047001614700224E068-41856
chr2047004624702017E068-40063
chr2047054114705485E068-36595
chr2047055954705812E068-36268
chr2047058964705953E068-36127
chr2047059644706098E068-35982
chr2047072324707344E068-34736
chr2047902394790309E06848159
chr2047903244790841E06848244
chr2047908664791098E06848786
chr2047911744791533E06849094
chr2047915364791796E06849456
chr2046973584697408E069-44672
chr2046980324698104E069-43976
chr2046983014698410E069-43670
chr2046984684698521E069-43559
chr2046986024698669E069-43411
chr2046986894698847E069-43233
chr2046998864699926E069-42154
chr2046999854700067E069-42013
chr2047001614700224E069-41856
chr2047040604704100E069-37980
chr2047041814704254E069-37826
chr2047043874704486E069-37594
chr2047047364704820E069-37260
chr2047048794704924E069-37156
chr2047050934705233E069-36847
chr2047052574705345E069-36735
chr2047054114705485E069-36595
chr2047055954705812E069-36268
chr2047058964705953E069-36127
chr2047059644706098E069-35982
chr2047736194773674E06931539
chr2047863514786510E06944271
chr2047865494786703E06944469
chr2047867484787007E06944668
chr2047895734790051E06947493
chr2047902394790309E06948159
chr2047903244790841E06948244
chr2047908664791098E06948786
chr2047911744791533E06949094
chr2047915364791796E06949456
chr2047004624702017E070-40063
chr2047055954705812E070-36268
chr2047058964705953E070-36127
chr2047059644706098E070-35982
chr2047072324707344E070-34736
chr2046980324698104E071-43976
chr2046983014698410E071-43670
chr2046984684698521E071-43559
chr2046986024698669E071-43411
chr2046986894698847E071-43233
chr2046999854700067E071-42013
chr2047001614700224E071-41856
chr2047050934705233E071-36847
chr2047052574705345E071-36735
chr2047054114705485E071-36595
chr2047055954705812E071-36268
chr2047058964705953E071-36127
chr2047059644706098E071-35982
chr2047072324707344E071-34736
chr2047213004721941E071-20139
chr2047736194773674E07131539
chr2047738494773912E07131769
chr2047739164774057E07131836
chr2047861594786281E07144079
chr2047863514786510E07144271
chr2047865494786703E07144469
chr2047867484787007E07144668
chr2047895734790051E07147493
chr2047902394790309E07148159
chr2047903244790841E07148244
chr2047908664791098E07148786
chr2047911744791533E07149094
chr2047915364791796E07149456
chr2046986024698669E072-43411
chr2046986894698847E072-43233
chr2047001614700224E072-41856
chr2047004624702017E072-40063
chr2047054114705485E072-36595
chr2047055954705812E072-36268
chr2047058964705953E072-36127
chr2047059644706098E072-35982
chr2047072324707344E072-34736
chr2047081574708319E072-33761
chr2047736194773674E07231539
chr2047738494773912E07231769
chr2047865494786703E07244469
chr2047867484787007E07244668
chr2047895734790051E07247493
chr2047902394790309E07248159
chr2047903244790841E07248244
chr2047908664791098E07248786
chr2047911744791533E07249094
chr2047915364791796E07249456
chr2046980324698104E073-43976
chr2046983014698410E073-43670
chr2046984684698521E073-43559
chr2046986024698669E073-43411
chr2046986894698847E073-43233
chr2047001614700224E073-41856
chr2047004624702017E073-40063
chr2047040604704100E073-37980
chr2047041814704254E073-37826
chr2047043874704486E073-37594
chr2047902394790309E07348159
chr2047903244790841E07348244
chr2047908664791098E07348786
chr2047911744791533E07349094
chr2047915364791796E07349456
chr2046983014698410E074-43670
chr2046984684698521E074-43559
chr2046986024698669E074-43411
chr2046986894698847E074-43233
chr2047001614700224E074-41856
chr2047004624702017E074-40063
chr2047072324707344E074-34736
chr2047213004721941E074-20139
chr2047736194773674E07431539
chr2047738494773912E07431769
chr2047739164774057E07431836
chr2047863514786510E07444271
chr2047865494786703E07444469
chr2047867484787007E07444668
chr2047882504788300E07446170
chr2047885844788831E07446504
chr2047895734790051E07447493
chr2047902394790309E07448159
chr2047903244790841E07448244
chr2047908664791098E07448786
chr2047911744791533E07449094
chr2047915364791796E07449456
chr2047020554702124E081-39956
chr2047021744702283E081-39797
chr2047054114705485E081-36595
chr2047055954705812E081-36268
chr2047087494709460E081-32620
chr2047571264757401E08115046
chr2047577574757829E08115677
chr2047599064759967E08117826
chr2047600144760068E08117934
chr2047603924760526E08118312
chr2047004624702017E082-40063










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr2047563404756468E06714260
chr2047564824756532E06714402
chr2047566554756709E06714575
chr2047563404756468E06814260
chr2047564824756532E06814402
chr2047566554756709E06814575
chr2047563404756468E06914260
chr2047564824756532E06914402
chr2047566554756709E06914575
chr2047563404756468E07114260
chr2047564824756532E07114402
chr2047566554756709E07114575
chr2047563404756468E07214260
chr2047564824756532E07214402
chr2047566554756709E07214575
chr2047563404756468E07314260
chr2047564824756532E07314402
chr2047566554756709E07314575
chr2047563404756468E07414260
chr2047564824756532E07414402
chr2047566554756709E07414575