rs970674

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0067 (2024/29986,GnomAD)
A=0071 (2077/29118,TOPMED)
A=0104 (520/5008,1000G)
A=0038 (147/3854,ALSPAC)
A=0039 (145/3708,TWINSUK)
chr4:146629922 (GRCh38.p7) (4q31.22)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
41 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.146629922G>A
GRCh37.p13 chr 4NC_000004.11:g.147551074G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.921A=0.079
1000GenomesAmericanSub694G=0.900A=0.100
1000GenomesEast AsianSub1008G=0.758A=0.242
1000GenomesEuropeSub1006G=0.954A=0.046
1000GenomesGlobalStudy-wide5008G=0.896A=0.104
1000GenomesSouth AsianSub978G=0.940A=0.060
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.962A=0.038
The Genome Aggregation DatabaseAfricanSub8734G=0.938A=0.062
The Genome Aggregation DatabaseAmericanSub838G=0.890A=0.110
The Genome Aggregation DatabaseEast AsianSub1620G=0.749A=0.251
The Genome Aggregation DatabaseEuropeSub18492G=0.948A=0.051
The Genome Aggregation DatabaseGlobalStudy-wide29986G=0.932A=0.067
The Genome Aggregation DatabaseOtherSub302G=0.920A=0.080
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.928A=0.071
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.961A=0.039
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs9706740.00077alcohol dependence(early age of onset)20201924
rs9706740.00097alcohol dependence20201924

eQTL of rs970674 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs970674 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr4147559421147559805E0678347
chr4147575632147575800E06724558
chr4147575873147576292E06724799
chr4147576294147576898E06725220
chr4147559808147559977E0688734
chr4147560013147560454E0688939
chr4147575632147575800E06824558
chr4147575873147576292E06824799
chr4147576294147576898E06825220
chr4147559176147559286E0698102
chr4147559421147559805E0698347
chr4147559808147559977E0698734
chr4147560013147560454E0698939
chr4147575873147576292E06924799
chr4147576294147576898E06925220
chr4147575632147575800E07024558
chr4147559808147559977E0718734
chr4147560013147560454E0718939
chr4147575632147575800E07124558
chr4147575873147576292E07124799
chr4147576294147576898E07125220
chr4147559176147559286E0728102
chr4147559421147559805E0728347
chr4147560013147560454E0728939
chr4147575632147575800E07224558
chr4147575873147576292E07224799
chr4147576294147576898E07225220
chr4147560013147560454E0738939
chr4147575632147575800E07324558
chr4147575873147576292E07324799
chr4147576294147576898E07325220
chr4147559421147559805E0748347
chr4147559808147559977E0748734
chr4147560013147560454E0748939
chr4147575632147575800E07424558
chr4147575873147576292E07424799
chr4147576294147576898E07425220
chr4147559808147559977E0828734
chr4147560013147560454E0828939
chr4147575873147576292E08224799
chr4147576294147576898E08225220