SNP Detail Info-rs970674

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0067 (2024/29986,GnomAD)
A=0071 (2077/29118,TOPMED)
A=0104 (520/5008,1000G)
A=0038 (147/3854,ALSPAC)
A=0039 (145/3708,TWINSUK)

Position: chr4:146629922 (GRCh38.p7) (4q31.22)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 41 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 4	NC_000004.12:g.146629922G>A
GRCh37.p13 chr 4	NC_000004.11:g.147551074G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.921	A=0.079
1000Genomes	American	Sub	694	G=0.900	A=0.100
1000Genomes	East Asian	Sub	1008	G=0.758	A=0.242
1000Genomes	Europe	Sub	1006	G=0.954	A=0.046
1000Genomes	Global	Study-wide	5008	G=0.896	A=0.104
1000Genomes	South Asian	Sub	978	G=0.940	A=0.060
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.962	A=0.038
The Genome Aggregation Database	African	Sub	8734	G=0.938	A=0.062
The Genome Aggregation Database	American	Sub	838	G=0.890	A=0.110
The Genome Aggregation Database	East Asian	Sub	1620	G=0.749	A=0.251
The Genome Aggregation Database	Europe	Sub	18492	G=0.948	A=0.051
The Genome Aggregation Database	Global	Study-wide	29986	G=0.932	A=0.067
The Genome Aggregation Database	Other	Sub	302	G=0.920	A=0.080
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.928	A=0.071
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.961	A=0.039

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs970674	0.00077	alcohol dependence(early age of onset)	20201924
rs970674	0.00097	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr4	147559421	147559805	E067	8347
chr4	147575632	147575800	E067	24558
chr4	147575873	147576292	E067	24799
chr4	147576294	147576898	E067	25220
chr4	147559808	147559977	E068	8734
chr4	147560013	147560454	E068	8939
chr4	147575632	147575800	E068	24558
chr4	147575873	147576292	E068	24799
chr4	147576294	147576898	E068	25220
chr4	147559176	147559286	E069	8102
chr4	147559421	147559805	E069	8347
chr4	147559808	147559977	E069	8734
chr4	147560013	147560454	E069	8939
chr4	147575873	147576292	E069	24799
chr4	147576294	147576898	E069	25220
chr4	147575632	147575800	E070	24558
chr4	147559808	147559977	E071	8734
chr4	147560013	147560454	E071	8939
chr4	147575632	147575800	E071	24558
chr4	147575873	147576292	E071	24799
chr4	147576294	147576898	E071	25220
chr4	147559176	147559286	E072	8102
chr4	147559421	147559805	E072	8347
chr4	147560013	147560454	E072	8939
chr4	147575632	147575800	E072	24558
chr4	147575873	147576292	E072	24799
chr4	147576294	147576898	E072	25220
chr4	147560013	147560454	E073	8939
chr4	147575632	147575800	E073	24558
chr4	147575873	147576292	E073	24799
chr4	147576294	147576898	E073	25220
chr4	147559421	147559805	E074	8347
chr4	147559808	147559977	E074	8734
chr4	147560013	147560454	E074	8939
chr4	147575632	147575800	E074	24558
chr4	147575873	147576292	E074	24799
chr4	147576294	147576898	E074	25220
chr4	147559808	147559977	E082	8734
chr4	147560013	147560454	E082	8939
chr4	147575873	147576292	E082	24799
chr4	147576294	147576898	E082	25220

rs970674