rs979537

Homo sapiens
T>C
LOC105377981 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0459 (13756/29908,GnomAD)
C=0490 (14280/29118,TOPMED)
T==0444 (2224/5008,1000G)
C=0381 (1468/3854,ALSPAC)
C=0389 (1444/3708,TWINSUK)
chr6:123661921 (GRCh38.p7) (6q22.31)
AD
GWASdb2
1   publication(s)
See rs on genome
6 Enhancers around
9 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.123661921T>C
GRCh37.p13 chr 6NC_000006.11:g.123983066T>C

Gene: LOC105377981, uncharacterized LOC105377981(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105377981 transcriptXR_942943.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.347C=0.653
1000GenomesAmericanSub694T=0.460C=0.540
1000GenomesEast AsianSub1008T=0.298C=0.702
1000GenomesEuropeSub1006T=0.649C=0.351
1000GenomesGlobalStudy-wide5008T=0.444C=0.556
1000GenomesSouth AsianSub978T=0.500C=0.500
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.619C=0.381
The Genome Aggregation DatabaseAfricanSub8700T=0.387C=0.613
The Genome Aggregation DatabaseAmericanSub838T=0.440C=0.560
The Genome Aggregation DatabaseEast AsianSub1608T=0.335C=0.665
The Genome Aggregation DatabaseEuropeSub18460T=0.633C=0.366
The Genome Aggregation DatabaseGlobalStudy-wide29908T=0.540C=0.459
The Genome Aggregation DatabaseOtherSub302T=0.620C=0.380
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.509C=0.490
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.611C=0.389
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs9795376.8E-05alcoholism (heaviness of drinking)21529783

eQTL of rs979537 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs979537 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr6123959478123959551E068-23515
chr6123959749123959799E068-23267
chr6123960164123960238E068-22828
chr6124015118124015236E08132052
chr6124015286124015837E08132220
chr6124016026124016120E08132960


Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr6123976707123976953E067-6113
chr6123977178123977281E067-5785
chr6123976707123976953E068-6113
chr6123977178123977281E068-5785
chr6123976707123976953E069-6113
chr6123976707123976953E071-6113
chr6123976707123976953E072-6113
chr6123977178123977281E072-5785
chr6123976707123976953E074-6113