rs980772

Homo sapiens
G>A / G>T
TEX41 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G==0396 (11853/29918,GnomAD)
G==0405 (11811/29118,TOPMED)
G==0374 (1875/5008,1000G)
G==0334 (1288/3854,ALSPAC)
G==0330 (1223/3708,TWINSUK)
chr2:144684623 (GRCh38.p7) (2q22.3)
AD
GWASdb2
1   publication(s)
See rs on genome
8 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.144684623G>A
GRCh38.p7 chr 2NC_000002.12:g.144684623G>T
GRCh37.p13 chr 2NC_000002.11:g.145442190G>A
GRCh37.p13 chr 2NC_000002.11:g.145442190G>T

Gene: TEX41, testis expressed 41 (non-protein coding)(plus strand)

Molecule type Change Amino acid[Codon] SO Term
TEX41 transcriptNR_033870.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.599T=0.401
1000GenomesAmericanSub694G=0.280T=0.720
1000GenomesEast AsianSub1008G=0.222T=0.778
1000GenomesEuropeSub1006G=0.349T=0.651
1000GenomesGlobalStudy-wide5008G=0.374T=0.626
1000GenomesSouth AsianSub978G=0.320T=0.680
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.334T=0.666
The Genome Aggregation DatabaseAfricanSub8694G=0.552T=0.448
The Genome Aggregation DatabaseAmericanSub836G=0.240T=0.760
The Genome Aggregation DatabaseEast AsianSub1616G=0.197T=0.803
The Genome Aggregation DatabaseEuropeSub18474G=0.348T=0.651
The Genome Aggregation DatabaseGlobalStudy-wide29918G=0.396T=0.603
The Genome Aggregation DatabaseOtherSub298G=0.330T=0.670
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.405T=0.594
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.330T=0.670
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs9807720.000804alcohol consumption (maxi-drinks)24277619

eQTL of rs980772 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs980772 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2145528417145529210E0674171
chr2145533155145533236E0688909
chr2145533386145534023E0689140
chr2145553727145553781E06829481
chr2145528417145529210E0704171
chr2145528417145529210E0714171
chr2145528417145529210E0744171
chr2145555477145556040E08231231