rs981146

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0435 (13013/29886,GnomAD)
C==0469 (13678/29118,TOPMED)
C==0360 (1803/5008,1000G)
C==0426 (1642/3854,ALSPAC)
C==0422 (1566/3708,TWINSUK)
chr6:68461016 (GRCh38.p7) (6q12)
ND
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.68461016C>T
GRCh37.p13 chr 6NC_000006.11:g.69170908C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.579T=0.421
1000GenomesAmericanSub694C=0.300T=0.700
1000GenomesEast AsianSub1008C=0.103T=0.897
1000GenomesEuropeSub1006C=0.397T=0.603
1000GenomesGlobalStudy-wide5008C=0.360T=0.640
1000GenomesSouth AsianSub978C=0.330T=0.670
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.426T=0.574
The Genome Aggregation DatabaseAfricanSub8696C=0.545T=0.455
The Genome Aggregation DatabaseAmericanSub830C=0.310T=0.690
The Genome Aggregation DatabaseEast AsianSub1616C=0.102T=0.898
The Genome Aggregation DatabaseEuropeSub18442C=0.419T=0.581
The Genome Aggregation DatabaseGlobalStudy-wide29886C=0.435T=0.564
The Genome Aggregation DatabaseOtherSub302C=0.400T=0.600
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.469T=0.530
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.422T=0.578
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs9811460.00077nicotine dependence17158188

eQTL of rs981146 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs981146 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.