rs9836784

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

ZNF385D : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0197 (5893/29850,GnomAD)
A=0216 (6315/29118,TOPMED)
A=0197 (985/5008,1000G)
A=0231 (891/3854,ALSPAC)
A=0231 (858/3708,TWINSUK)

Position: chr3:21841499 (GRCh38.p7) (3p24.3)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Variant Details Frequency Publications p-values eSNP meSNP

Genomic Coordinates

Sequence Name	Change(s)
GRCh38.p7 chr 3	NC_000003.12:g.21841499G>A
GRCh37.p13 chr 3	NC_000003.11:g.21882991G>A

Gene: ZNF385D, zinc finger protein 385D(minus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
ZNF385D transcript	NM_024697.2:c.	N/A	Genic Upstream Transcript Variant
ZNF385D transcript variant X12	XM_011534122.1:c.	N/A	Intron Variant
ZNF385D transcript variant X13	XM_011534123.2:c.	N/A	Intron Variant
ZNF385D transcript variant X14	XM_011534124.2:c.	N/A	Intron Variant
ZNF385D transcript variant X1	XM_017007191.1:c.	N/A	Intron Variant
ZNF385D transcript variant X2	XM_017007192.1:c.	N/A	Intron Variant
ZNF385D transcript variant X3	XM_017007193.1:c.	N/A	Intron Variant
ZNF385D transcript variant X4	XM_017007194.1:c.	N/A	Intron Variant
ZNF385D transcript variant X5	XM_017007195.1:c.	N/A	Intron Variant
ZNF385D transcript variant X8	XM_017007198.1:c.	N/A	Intron Variant
ZNF385D transcript variant X9	XM_017007199.1:c.	N/A	Intron Variant
ZNF385D transcript variant X16	XM_017007203.1:c.	N/A	Intron Variant
ZNF385D transcript variant X6	XM_017007196.1:c.	N/A	Genic Upstream Transcript Variant
ZNF385D transcript variant X7	XM_017007197.1:c.	N/A	Genic Upstream Transcript Variant
ZNF385D transcript variant X10	XM_017007200.1:c.	N/A	Genic Upstream Transcript Variant
ZNF385D transcript variant X11	XM_017007201.1:c.	N/A	Genic Upstream Transcript Variant
ZNF385D transcript variant X15	XM_017007202.1:c.	N/A	Genic Upstream Transcript Variant

Population Frequency

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.817	A=0.183
1000Genomes	American	Sub	694	G=0.740	A=0.260
1000Genomes	East Asian	Sub	1008	G=0.827	A=0.173
1000Genomes	Europe	Sub	1006	G=0.797	A=0.203
1000Genomes	Global	Study-wide	5008	G=0.803	A=0.197
1000Genomes	South Asian	Sub	978	G=0.810	A=0.190
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.769	A=0.231
The Genome Aggregation Database	African	Sub	8706	G=0.801	A=0.199
The Genome Aggregation Database	American	Sub	838	G=0.740	A=0.260
The Genome Aggregation Database	East Asian	Sub	1566	G=0.824	A=0.176
The Genome Aggregation Database	Europe	Sub	18438	G=0.806	A=0.193
The Genome Aggregation Database	Global	Study-wide	29850	G=0.802	A=0.197
The Genome Aggregation Database	Other	Sub	302	G=0.690	A=0.310
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.783	A=0.216
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.769	A=0.231

PMID	Title	Author	Journal
19581569	Genome-wide association study of alcohol dependence.	Treutlein J	Arch Gen Psychiatry

P-Value

SNP ID	p-value	Traits	Study
rs9836784	7.48E-05	alcohol dependence	19581569

eQTL of rs9836784 in Brain tissues (GTEx Analysis Release V7)

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

meQTL of rs9836784 in Fetal Brain

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.