rs9845140

Homo sapiens
C>A
None
Check p-value
SNV (Single Nucleotide Variation)
C==0246 (7358/29904,GnomAD)
C==0201 (5874/29118,TOPMED)
C==0310 (1553/5008,1000G)
C==0266 (1027/3854,ALSPAC)
C==0266 (986/3708,TWINSUK)
chr3:18687386 (GRCh38.p7) (3p24.3)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.18687386C>A
GRCh37.p13 chr 3NC_000003.11:g.18728878C>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.085A=0.915
1000GenomesAmericanSub694C=0.260A=0.740
1000GenomesEast AsianSub1008C=0.499A=0.501
1000GenomesEuropeSub1006C=0.297A=0.703
1000GenomesGlobalStudy-wide5008C=0.310A=0.690
1000GenomesSouth AsianSub978C=0.470A=0.530
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.266A=0.734
The Genome Aggregation DatabaseAfricanSub8718C=0.114A=0.886
The Genome Aggregation DatabaseAmericanSub834C=0.250A=0.750
The Genome Aggregation DatabaseEast AsianSub1606C=0.508A=0.492
The Genome Aggregation DatabaseEuropeSub18444C=0.283A=0.716
The Genome Aggregation DatabaseGlobalStudy-wide29904C=0.246A=0.753
The Genome Aggregation DatabaseOtherSub302C=0.390A=0.610
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.201A=0.798
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.266A=0.734
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs98451400.00017alcohol dependence20201924

eQTL of rs9845140 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs9845140 in Fetal Brain

Probe ID Position Gene beta p-value
cg10792120chr13:78550373EDNRB0.01722545013336529.6147e-9

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.