rs9874556

Homo sapiens
A>G
LOC100130207 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A==0446 (13327/29884,GnomAD)
A==0477 (13890/29118,TOPMED)
A==0352 (1763/5008,1000G)
G=0499 (1922/3854,ALSPAC)
A==0491 (1820/3708,TWINSUK)
chr3:3314490 (GRCh38.p7) (3p26.2)
AD
GWASdb2 | GWASCatalog
1   publication(s)
See rs on genome
4 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.3314490A>G
GRCh37.p13 chr 3NC_000003.11:g.3356174A>G

Gene: LOC100130207, uncharacterized LOC100130207(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC100130207 transcript variant X2XR_001740402.1:n.N/AIntron Variant
LOC100130207 transcript variant X1XR_001740401.1:n.N/AGenic Downstream Transcript Variant
LOC100130207 transcript variant X3XR_001740403.1:n.N/AGenic Downstream Transcript Variant
LOC100130207 transcript variant X4XR_001740404.1:n.N/AGenic Downstream Transcript Variant
LOC100130207 transcript variant X5XR_001740405.1:n.N/AGenic Downstream Transcript Variant
LOC100130207 transcript variant X6XR_001740406.1:n.N/AGenic Downstream Transcript Variant
LOC100130207 transcript variant X7XR_001740407.1:n.N/AGenic Downstream Transcript Variant
LOC100130207 transcript variant X8XR_001740408.1:n.N/AGenic Downstream Transcript Variant
LOC100130207 transcript variant X9XR_001740409.1:n.N/AGenic Downstream Transcript Variant
LOC100130207 transcript variant X10XR_001740410.1:n.N/AGenic Downstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.501G=0.499
1000GenomesAmericanSub694A=0.360G=0.640
1000GenomesEast AsianSub1008A=0.036G=0.964
1000GenomesEuropeSub1006A=0.476G=0.524
1000GenomesGlobalStudy-wide5008A=0.352G=0.648
1000GenomesSouth AsianSub978A=0.350G=0.650
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.501G=0.499
The Genome Aggregation DatabaseAfricanSub8702A=0.473G=0.527
The Genome Aggregation DatabaseAmericanSub832A=0.370G=0.630
The Genome Aggregation DatabaseEast AsianSub1612A=0.011G=0.989
The Genome Aggregation DatabaseEuropeSub18436A=0.474G=0.525
The Genome Aggregation DatabaseGlobalStudy-wide29884A=0.446G=0.554
The Genome Aggregation DatabaseOtherSub302A=0.470G=0.530
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.477G=0.523
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.491G=0.509
PMID Title Author Journal
24962325Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.Kapoor MDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs98745569E-06alcohol dependence (age at onset)24962325

eQTL of rs9874556 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs9874556 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr333975333397824E07041359
chr333980273399048E07041853
chr333990973399382E07042923
chr333997333399783E07043559