rs9881405

Homo sapiens
G>T
SRPRB : Intron Variant
LOC105374116 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0191 (5737/29936,GnomAD)
T=0175 (5107/29118,TOPMED)
T=0169 (844/5008,1000G)
T=0261 (1005/3854,ALSPAC)
T=0258 (955/3708,TWINSUK)
chr3:133799354 (GRCh38.p7) (3q22.1)
AD
GWASdb2
1   publication(s)
See rs on genome
62 Enhancers around
26 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.133799354G>T
GRCh37.p13 chr 3NC_000003.11:g.133518198G>T

Gene: SRPRB, SRP receptor beta subunit(plus strand)

Molecule type Change Amino acid[Codon] SO Term
SRPRB transcriptNM_021203.3:c.N/AIntron Variant

Gene: LOC105374116, uncharacterized LOC105374116(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105374116 transcript variant X1XR_924512.2:n.N/AIntron Variant
LOC105374116 transcript variant X2XR_924513.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.919T=0.081
1000GenomesAmericanSub694G=0.780T=0.220
1000GenomesEast AsianSub1008G=0.774T=0.226
1000GenomesEuropeSub1006G=0.801T=0.199
1000GenomesGlobalStudy-wide5008G=0.831T=0.169
1000GenomesSouth AsianSub978G=0.840T=0.160
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.739T=0.261
The Genome Aggregation DatabaseAfricanSub8718G=0.887T=0.113
The Genome Aggregation DatabaseAmericanSub836G=0.810T=0.190
The Genome Aggregation DatabaseEast AsianSub1612G=0.780T=0.220
The Genome Aggregation DatabaseEuropeSub18468G=0.775T=0.224
The Genome Aggregation DatabaseGlobalStudy-wide29936G=0.808T=0.191
The Genome Aggregation DatabaseOtherSub302G=0.690T=0.310
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.824T=0.175
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.742T=0.258
PMID Title Author Journal
21665994Genome-wide association study identifies two loci strongly affecting transferrin glycosylation.Kutalik ZHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs98814053.71E-13alcohol consumption21665994

eQTL of rs9881405 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs9881405 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr3133482923133483028E067-35170
chr3133483054133483594E067-34604
chr3133483998133484070E067-34128
chr3133562885133562960E06744687
chr3133482562133482616E068-35582
chr3133482923133483028E068-35170
chr3133483054133483594E068-34604
chr3133473014133473073E069-45125
chr3133473315133473659E069-44539
chr3133476260133476458E069-41740
chr3133482562133482616E069-35582
chr3133482923133483028E069-35170
chr3133483054133483594E069-34604
chr3133483998133484070E069-34128
chr3133484337133484387E069-33811
chr3133540603133541021E06922405
chr3133541191133541245E06922993
chr3133482923133483028E070-35170
chr3133483054133483594E070-34604
chr3133547093133547193E07028895
chr3133547516133547745E07029318
chr3133547924133548172E07029726
chr3133473014133473073E071-45125
chr3133473315133473659E071-44539
chr3133482562133482616E071-35582
chr3133482923133483028E071-35170
chr3133483054133483594E071-34604
chr3133483998133484070E071-34128
chr3133484337133484387E071-33811
chr3133540337133540417E07122139
chr3133473014133473073E072-45125
chr3133482923133483028E072-35170
chr3133483054133483594E072-34604
chr3133483998133484070E072-34128
chr3133484337133484387E072-33811
chr3133482923133483028E073-35170
chr3133483054133483594E073-34604
chr3133540006133540074E07321808
chr3133540337133540417E07322139
chr3133540603133541021E07322405
chr3133541035133541081E07322837
chr3133541191133541245E07322993
chr3133473014133473073E074-45125
chr3133473315133473659E074-44539
chr3133476260133476458E074-41740
chr3133482562133482616E074-35582
chr3133482923133483028E074-35170
chr3133483054133483594E074-34604
chr3133483998133484070E074-34128
chr3133484337133484387E074-33811
chr3133540006133540074E07421808
chr3133540337133540417E07422139
chr3133540603133541021E07422405
chr3133541035133541081E07422837
chr3133541191133541245E07422993
chr3133541431133541497E07423233
chr3133541623133541762E07423425
chr3133541910133541964E07423712
chr3133526132133526214E0817934
chr3133547516133547745E08229318
chr3133547924133548172E08229726
chr3133548284133548391E08230086










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr3133468272133468322E067-49876
chr3133524082133525550E0675884
chr3133525588133525634E0677390
chr3133468272133468322E068-49876
chr3133524082133525550E0685884
chr3133525588133525634E0687390
chr3133468272133468322E069-49876
chr3133524082133525550E0695884
chr3133524082133525550E0705884
chr3133525588133525634E0707390
chr3133468272133468322E071-49876
chr3133524082133525550E0715884
chr3133525588133525634E0717390
chr3133468272133468322E072-49876
chr3133524082133525550E0725884
chr3133525588133525634E0727390
chr3133468272133468322E073-49876
chr3133524082133525550E0735884
chr3133525588133525634E0737390
chr3133468272133468322E074-49876
chr3133524082133525550E0745884
chr3133525588133525634E0747390
chr3133524082133525550E0815884
chr3133525588133525634E0817390
chr3133524082133525550E0825884
chr3133525588133525634E0827390