rs990324

Homo sapiens
A>G
LINC00423 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G=0182 (5456/29958,GnomAD)
G=0255 (7425/29116,TOPMED)
G=0190 (951/5008,1000G)
G=0079 (306/3854,ALSPAC)
G=0081 (301/3708,TWINSUK)
chr13:32813108 (GRCh38.p7) (13q13.1)
AD
GWASdb2
1   publication(s)
See rs on genome
35 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 13NC_000013.11:g.32813108A>G
GRCh37.p13 chr 13NC_000013.10:g.33387246A>G

Gene: LINC00423, long intergenic non-protein coding RNA 423(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LINC00423 transcriptNR_047020.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.517G=0.483
1000GenomesAmericanSub694A=0.910G=0.090
1000GenomesEast AsianSub1008A=0.973G=0.027
1000GenomesEuropeSub1006A=0.911G=0.089
1000GenomesGlobalStudy-wide5008A=0.810G=0.190
1000GenomesSouth AsianSub978A=0.870G=0.130
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.921G=0.079
The Genome Aggregation DatabaseAfricanSub8706A=0.552G=0.448
The Genome Aggregation DatabaseAmericanSub834A=0.900G=0.100
The Genome Aggregation DatabaseEast AsianSub1620A=0.975G=0.025
The Genome Aggregation DatabaseEuropeSub18496A=0.924G=0.075
The Genome Aggregation DatabaseGlobalStudy-wide29958A=0.817G=0.182
The Genome Aggregation DatabaseOtherSub302A=0.880G=0.120
Trans-Omics for Precision MedicineGlobalStudy-wide29116A=0.745G=0.255
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.919G=0.081
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs9903242E-05alcoholism (heaviness of drinking)21529783

eQTL of rs990324 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs990324 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr133341507433415998E06827828
chr133342073833420963E06833492
chr133342096733421214E06833721
chr133339572133395791E0708475
chr133339588733395938E0708641
chr133339692133397238E0709675
chr133339724933397638E07010003
chr133339772333397778E07010477
chr133339788633398002E07010640
chr133339813933398199E07010893
chr133339825133398640E07011005
chr133341406133414138E07026815
chr133341425333414406E07027007
chr133341441333414477E07027167
chr133341448633414650E07027240
chr133341507433415998E07027828
chr133340487633404930E07217630
chr133341507433415998E07227828
chr133341242833413663E07325182
chr133341370533413755E07326459
chr133341406133414138E07326815
chr133341425333414406E07327007
chr133341441333414477E07327167
chr133341448633414650E07327240
chr133342440933424570E07337163
chr133342457833424747E07337332
chr133341425333414406E07427007
chr133341441333414477E07427167
chr133341448633414650E07427240
chr133339692133397238E0819675
chr133339724933397638E08110003
chr133339772333397778E08110477
chr133339788633398002E08110640
chr133339813933398199E08110893
chr133340353533404792E08216289