SNP Detail Info-rs9908966

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

SLFN5 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G==0406 (12114/29806,GnomAD)
G==0390 (11365/29118,TOPMED)
G==0439 (2199/5008,1000G)
G==0372 (1434/3854,ALSPAC)
G==0371 (1374/3708,TWINSUK)

Position: chr17:35256583 (GRCh38.p7) (17q12)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 22 Enhancers around

Promoter: 8 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 17	NC_000017.11:g.35256583G>A
GRCh37.p13 chr 17	NC_000017.10:g.33583602G>A

Molecule type	Change	Amino acid[Codon]	SO Term
SLFN5 transcript variant 1	NM_144975.3:c.	N/A	Intron Variant
SLFN5 transcript variant X1	XM_005257934.3:c.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.413	A=0.587
1000Genomes	American	Sub	694	G=0.410	A=0.590
1000Genomes	East Asian	Sub	1008	G=0.586	A=0.414
1000Genomes	Europe	Sub	1006	G=0.373	A=0.627
1000Genomes	Global	Study-wide	5008	G=0.439	A=0.561
1000Genomes	South Asian	Sub	978	G=0.410	A=0.590
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.372	A=0.628
The Genome Aggregation Database	African	Sub	8672	G=0.391	A=0.609
The Genome Aggregation Database	American	Sub	834	G=0.460	A=0.540
The Genome Aggregation Database	East Asian	Sub	1608	G=0.565	A=0.435
The Genome Aggregation Database	Europe	Sub	18390	G=0.398	A=0.601
The Genome Aggregation Database	Global	Study-wide	29806	G=0.406	A=0.593
The Genome Aggregation Database	Other	Sub	302	G=0.310	A=0.690
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.390	A=0.609
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.371	A=0.629

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs9908966	0.00091	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr17	33583602	33583988	E069	0
chr17	33579615	33579659	E071	-3943
chr17	33579724	33580014	E071	-3588
chr17	33580264	33580325	E071	-3277
chr17	33580501	33580567	E071	-3035
chr17	33580769	33580905	E071	-2697
chr17	33580947	33581012	E071	-2590
chr17	33581123	33581177	E071	-2425
chr17	33581197	33581779	E071	-1823
chr17	33582278	33582318	E071	-1284
chr17	33582335	33582402	E071	-1200
chr17	33582467	33582651	E071	-951
chr17	33584124	33584705	E071	522
chr17	33591224	33591264	E071	7622
chr17	33591930	33591996	E071	8328
chr17	33592044	33592112	E071	8442
chr17	33592284	33592642	E071	8682
chr17	33592654	33593107	E071	9052
chr17	33593271	33593339	E071	9669
chr17	33593373	33593423	E071	9771
chr17	33582335	33582402	E081	-1200
chr17	33582467	33582651	E081	-951

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr17	33568821	33572764	E067	-10838
chr17	33568821	33572764	E068	-10838
chr17	33568821	33572764	E069	-10838
chr17	33568821	33572764	E071	-10838
chr17	33568821	33572764	E072	-10838
chr17	33568821	33572764	E073	-10838
chr17	33568821	33572764	E074	-10838
chr17	33568821	33572764	E082	-10838

rs9908966