rs9927040

Homo sapiens
T>G
None
Check p-value
SNV (Single Nucleotide Variation)
T==0022 (679/29930,GnomAD)
T==0030 (886/29118,TOPMED)
T==0027 (136/5008,1000G)
T==0019 (75/3854,ALSPAC)
T==0019 (71/3708,TWINSUK)
chr16:7716853 (GRCh38.p7) (16p13.3)
ND
GWASdb2
1   publication(s)
See rs on genome
42 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 16NC_000016.10:g.7716853T>G
GRCh37.p13 chr 16NC_000016.9:g.7766855T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.061G=0.939
1000GenomesAmericanSub694T=0.020G=0.980
1000GenomesEast AsianSub1008T=0.000G=1.000
1000GenomesEuropeSub1006T=0.020G=0.980
1000GenomesGlobalStudy-wide5008T=0.027G=0.973
1000GenomesSouth AsianSub978T=0.020G=0.980
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.019G=0.981
The Genome Aggregation DatabaseAfricanSub8710T=0.048G=0.952
The Genome Aggregation DatabaseAmericanSub838T=0.020G=0.980
The Genome Aggregation DatabaseEast AsianSub1612T=0.000G=1.000
The Genome Aggregation DatabaseEuropeSub18468T=0.012G=0.987
The Genome Aggregation DatabaseGlobalStudy-wide29930T=0.022G=0.977
The Genome Aggregation DatabaseOtherSub302T=0.050G=0.950
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.030G=0.969
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.019G=0.981
PMID Title Author Journal
19268276Genome-wide association study of smoking initiation and current smoking.Vink JMAm J Hum Genet

P-Value

SNP ID p-value Traits Study
rs99270402.89E-05nicotine smoking19268276

eQTL of rs9927040 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs9927040 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1677816877781773E06714832
chr1677945607795609E06727705
chr1677959737796042E06729118
chr1677945607795609E06827705
chr1677959737796042E06829118
chr1677945607795609E06927705
chr1677959737796042E06929118
chr1677945607795609E07027705
chr1677959737796042E07029118
chr1677965277796665E07029672
chr1677966967796782E07029841
chr1677969387797313E07030083
chr1678056867805786E07038831
chr1677945607795609E07127705
chr1677945607795609E07227705
chr1677942627794314E07327407
chr1677945607795609E07327705
chr1677959737796042E07329118
chr1677945607795609E07427705
chr1677649067765006E081-1849
chr1677653517765405E081-1450
chr1677655267765602E081-1253
chr1677661697766289E081-566
chr1677667107766833E081-22
chr1677669157766984E08160
chr1677670147767145E081159
chr1677671747767409E081319
chr1677676597767888E081804
chr1677945607795609E08127705
chr1677959737796042E08129118
chr1677965277796665E08129672
chr1677966967796782E08129841
chr1677969387797313E08130083
chr1677649067765006E082-1849
chr1677661697766289E082-566
chr1677667107766833E082-22
chr1677669157766984E08260
chr1677670147767145E082159
chr1677671747767409E082319
chr1677691397769189E0822284
chr1677945607795609E08227705
chr1677969387797313E08230083