rs9927571

Homo sapiens
G>A / G>T
CDYL2 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0385 (11545/29916,GnomAD)
T=0458 (13355/29118,TOPMED)
T=0449 (2249/5008,1000G)
chr16:80623069 (GRCh38.p7) (16q23.2)
AD
GWASdb2
1   publication(s)
See rs on genome
124 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 16NC_000016.10:g.80623069G>A
GRCh38.p7 chr 16NC_000016.10:g.80623069G>T
GRCh37.p13 chr 16NC_000016.9:g.80656966G>A
GRCh37.p13 chr 16NC_000016.9:g.80656966G>T

Gene: CDYL2, chromodomain protein, Y-like 2(minus strand)

Molecule type Change Amino acid[Codon] SO Term
CDYL2 transcriptNM_152342.3:c.N/AIntron Variant
CDYL2 transcript variant X1XM_011522866.1:c.N/AIntron Variant
CDYL2 transcript variant X2XM_011522867.2:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.225T=0.775
1000GenomesAmericanSub694G=0.510T=0.490
1000GenomesEast AsianSub1008G=0.665T=0.335
1000GenomesEuropeSub1006G=0.720T=0.280
1000GenomesGlobalStudy-wide5008G=0.551T=0.449
1000GenomesSouth AsianSub978G=0.730T=0.270
The Genome Aggregation DatabaseAfricanSub8694G=0.315T=0.685
The Genome Aggregation DatabaseAmericanSub838G=0.470T=0.53,
The Genome Aggregation DatabaseEast AsianSub1622G=0.672T=0.328
The Genome Aggregation DatabaseEuropeSub18460G=0.754T=0.245
The Genome Aggregation DatabaseGlobalStudy-wide29916G=0.614T=0.385
The Genome Aggregation DatabaseOtherSub302G=0.700T=0.30,
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.541T=0.458
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs99275710.00026alcohol dependence20201924

eQTL of rs9927571 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs9927571 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr162391640723916788E067-26014
chr162391681523916935E067-25867
chr162391879823919237E067-23565
chr162392015723920207E067-22595
chr162394244323942774E067-28
chr162395343923953708E06710637
chr162395395423954008E06711152
chr162395588523956052E06713083
chr162395640123956536E06713599
chr162395654123956607E06713739
chr162396232123962508E06719519
chr162396307123964485E06720269
chr162397341823973513E06730616
chr162397370923973759E06730907
chr162397395323974020E06731151
chr162397788723978791E06735085
chr162390296123903034E068-39768
chr162390315023903219E068-39583
chr162390325823903310E068-39492
chr162391247523913095E068-29707
chr162391315723913302E068-29500
chr162395112123951527E0688319
chr162395501723955110E06812215
chr162395588523956052E06813083
chr162395640123956536E06813599
chr162395654123956607E06813739
chr162395666123956751E06813859
chr162395675623956806E06813954
chr162395684223956991E06814040
chr162396019523962211E06817393
chr162396307123964485E06820269
chr162396469223964742E06821890
chr162396478823964889E06821986
chr162396495923965046E06822157
chr162397094923971125E06828147
chr162397112623971243E06828324
chr162397135023971775E06828548
chr162397788723978791E06835085
chr162398777223988386E06844970
chr162398842723988531E06845625
chr162398859623988636E06845794
chr162398885323988977E06846051
chr162398916023989221E06846358
chr162398952323989606E06846721
chr162399014323990183E06847341
chr162390315023903219E069-39583
chr162395395423954008E06911152
chr162395588523956052E06913083
chr162395640123956536E06913599
chr162395654123956607E06913739
chr162396232123962508E06919519
chr162396307123964485E06920269
chr162397788723978791E06935085
chr162397881523978924E06936013
chr162397930623979804E06936504
chr162397788723978791E07035085
chr162390296123903034E071-39768
chr162390315023903219E071-39583
chr162390325823903310E071-39492
chr162395588523956052E07113083
chr162395640123956536E07113599
chr162395654123956607E07113739
chr162396307123964485E07120269
chr162391640723916788E072-26014
chr162391681523916935E072-25867
chr162391879823919237E072-23565
chr162391949023919748E072-23054
chr162392015723920207E072-22595
chr162392028623920437E072-22365
chr162392048623920738E072-22064
chr162395343923953708E07210637
chr162395588523956052E07213083
chr162396307123964485E07220269
chr162397788723978791E07235085
chr162399103423991123E07248232
chr162399152023991594E07248718
chr162391609623916400E073-26402
chr162391640723916788E073-26014
chr162391681523916935E073-25867
chr162391879823919237E073-23565
chr162396307123964485E07320269
chr162397094923971125E07328147
chr162397112623971243E07328324
chr162397135023971775E07328548
chr162397187423972206E07329072
chr162397788723978791E07335085
chr162398594323985993E07343141
chr162398633023986395E07343528
chr162398777223988386E07344970
chr162398842723988531E07345625
chr162398859623988636E07345794
chr162398952323989606E07346721
chr162399014323990183E07347341
chr162395112123951527E0748319
chr162395588523956052E07413083
chr162396307123964485E07420269
chr162397052023970609E07427718
chr162397062623970860E07427824
chr162397094923971125E07428147
chr162397112623971243E07428324
chr162397135023971775E07428548
chr162397788723978791E07435085
chr162391433823914772E081-28030
chr162391491423914964E081-27838
chr162391510323915252E081-27550
chr162391542123915533E081-27269
chr162391556723915704E081-27098
chr162391681523916935E081-25867
chr162391721423917850E081-24952
chr162391797923918224E081-24578
chr162395588523956052E08113083
chr162395640123956536E08113599
chr162395654123956607E08113739
chr162395666123956751E08113859
chr162395675623956806E08113954
chr162396307123964485E08120269
chr162396469223964742E08121890
chr162396478823964889E08121986
chr162392600523926108E082-16694
chr162392611023926766E082-16036
chr162394221823942356E082-446
chr162394244323942774E082-28
chr162396232123962508E08219519
chr162396307123964485E08220269