rs9927767

Homo sapiens
T>A
ADCY9 : 2KB Upstream Variant
Check p-value
SNV (Single Nucleotide Variation)
T==0134 (4014/29950,GnomAD)
T==0176 (5132/29118,TOPMED)
T==0113 (568/5008,1000G)
T==0080 (308/3854,ALSPAC)
T==0083 (307/3708,TWINSUK)
chr16:4118169 (GRCh38.p7) (16p13.3)
AD
GWASdb2
1   publication(s)
See rs on genome
91 Enhancers around
17 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 16NC_000016.10:g.4118169T>A
GRCh37.p13 chr 16NC_000016.9:g.4168170T>A
ADCY9 RefSeqGeneNG_011434.1:g.3017A>T

Gene: ADCY9, adenylate cyclase 9(minus strand): 2KB Upstream Variant

Molecule type Change Amino acid[Codon] SO Term
ADCY9 transcriptNM_001116.3:c.N/AUpstream Transcript Variant
ADCY9 transcript variant X1XM_005255079.3:c.N/AN/A
ADCY9 transcript variant X2XM_011522353.2:c.N/AN/A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.316A=0.684
1000GenomesAmericanSub694T=0.070A=0.930
1000GenomesEast AsianSub1008T=0.002A=0.998
1000GenomesEuropeSub1006T=0.069A=0.931
1000GenomesGlobalStudy-wide5008T=0.113A=0.887
1000GenomesSouth AsianSub978T=0.030A=0.970
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.080A=0.920
The Genome Aggregation DatabaseAfricanSub8708T=0.280A=0.720
The Genome Aggregation DatabaseAmericanSub836T=0.050A=0.950
The Genome Aggregation DatabaseEast AsianSub1622T=0.000A=1.000
The Genome Aggregation DatabaseEuropeSub18484T=0.080A=0.919
The Genome Aggregation DatabaseGlobalStudy-wide29950T=0.134A=0.866
The Genome Aggregation DatabaseOtherSub300T=0.150A=0.850
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.176A=0.823
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.083A=0.917
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs99277670.000842alcohol dependence21314694

eQTL of rs9927767 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs9927767 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1641325914132755E067-35415
chr1641328544132908E067-35262
chr1641329744133043E067-35127
chr1641460144146621E067-21549
chr1641466304146896E067-21274
chr1641571414157238E067-10932
chr1641592604159870E067-8300
chr1641599094159986E067-8184
chr1641600594160356E067-7814
chr1641308974131439E068-36731
chr1641314554132058E068-36112
chr1641325914132755E068-35415
chr1641394144139880E068-28290
chr1641399354140841E068-27329
chr1641460144146621E068-21549
chr1641466304146896E068-21274
chr1641591034159157E068-9013
chr1641592604159870E068-8300
chr1641599094159986E068-8184
chr1641600594160356E068-7814
chr1641308974131439E069-36731
chr1641314554132058E069-36112
chr1641325914132755E069-35415
chr1641399354140841E069-27329
chr1641445084144592E069-23578
chr1641592604159870E069-8300
chr1641599094159986E069-8184
chr1641466304146896E070-21274
chr1641469344147001E070-21169
chr1641470934147296E070-20874
chr1641473794147458E070-20712
chr1641600594160356E070-7814
chr1641607454160958E070-7212
chr1641611794161231E070-6939
chr1641613344161401E070-6769
chr1641615144161676E070-6494
chr1641617784162012E070-6158
chr1641308974131439E071-36731
chr1641325914132755E071-35415
chr1641445084144592E071-23578
chr1641447774144833E071-23337
chr1641460144146621E071-21549
chr1641466304146896E071-21274
chr1641559284155982E071-12188
chr1641563984156448E071-11722
chr1641564974156557E071-11613
chr1641592604159870E071-8300
chr1641599094159986E071-8184
chr1641600594160356E071-7814
chr1641325914132755E072-35415
chr1641399354140841E072-27329
chr1641469344147001E072-21169
chr1641470934147296E072-20874
chr1641473794147458E072-20712
chr1641592604159870E072-8300
chr1641599094159986E072-8184
chr1641600594160356E072-7814
chr1641607454160958E072-7212
chr1641314554132058E073-36112
chr1641325914132755E073-35415
chr1641328544132908E073-35262
chr1641329744133043E073-35127
chr1641399354140841E073-27329
chr1641592604159870E073-8300
chr1641600594160356E073-7814
chr1641607454160958E073-7212
chr1641308974131439E074-36731
chr1641314554132058E074-36112
chr1641393124139406E074-28764
chr1641394144139880E074-28290
chr1641399354140841E074-27329
chr1641434554144492E074-23678
chr1641445084144592E074-23578
chr1641447774144833E074-23337
chr1641592604159870E074-8300
chr1641599094159986E074-8184
chr1641642154164307E074-3863
chr1641643754164457E074-3713
chr1641434554144492E081-23678
chr1641445084144592E081-23578
chr1641607454160958E081-7212
chr1641611794161231E081-6939
chr1641613344161401E081-6769
chr1641615144161676E081-6494
chr1641617784162012E081-6158
chr1641642154164307E081-3863
chr1641643754164457E081-3713
chr1641325914132755E082-35415
chr1641607454160958E082-7212
chr1641642154164307E082-3863
chr1641643754164457E082-3713










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr1641620384162978E067-5192
chr1641648834167621E067-549
chr1641620384162978E068-5192
chr1641648834167621E068-549
chr1641620384162978E069-5192
chr1641648834167621E069-549
chr1641620384162978E070-5192
chr1641648834167621E070-549
chr1641620384162978E071-5192
chr1641648834167621E071-549
chr1641620384162978E072-5192
chr1641648834167621E072-549
chr1641620384162978E073-5192
chr1641648834167621E073-549
chr1641648834167621E074-549
chr1641620384162978E082-5192
chr1641648834167621E082-549