rs9935277

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0221 (6615/29934,GnomAD)
G=0255 (7438/29118,TOPMED)
G=0219 (1096/5008,1000G)
G=0142 (548/3854,ALSPAC)
G=0136 (503/3708,TWINSUK)
chr16:24373390 (GRCh38.p7) (16p12.1)
AD
GWASdb2
1   publication(s)
See rs on genome
18 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 16NC_000016.10:g.24373390A>G
GRCh37.p13 chr 16NC_000016.9:g.24384711A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.528G=0.472
1000GenomesAmericanSub694A=0.910G=0.090
1000GenomesEast AsianSub1008A=0.904G=0.096
1000GenomesEuropeSub1006A=0.840G=0.160
1000GenomesGlobalStudy-wide5008A=0.781G=0.219
1000GenomesSouth AsianSub978A=0.850G=0.150
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.858G=0.142
The Genome Aggregation DatabaseAfricanSub8700A=0.592G=0.408
The Genome Aggregation DatabaseAmericanSub838A=0.900G=0.100
The Genome Aggregation DatabaseEast AsianSub1620A=0.924G=0.076
The Genome Aggregation DatabaseEuropeSub18474A=0.848G=0.151
The Genome Aggregation DatabaseGlobalStudy-wide29934A=0.779G=0.221
The Genome Aggregation DatabaseOtherSub302A=0.810G=0.190
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.744G=0.255
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.864G=0.136
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs99352770.000238alcohol dependence24277619

eQTL of rs9935277 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs9935277 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr162434049224340592E070-44119
chr162434385024344320E070-40391
chr162434436024344438E070-40273
chr162434538024345461E070-39250
chr162434552424345605E070-39106
chr162440493524405071E07020224
chr162440509324405202E07020382
chr162440569824405993E07020987
chr162440657724406678E07021866
chr162434007024340120E073-44591
chr162433574324335958E081-48753
chr162434049224340592E081-44119
chr162434385024344320E081-40391
chr162434436024344438E081-40273
chr162434611424346164E081-38547
chr162433574324335958E082-48753
chr162440509324405202E08220382
chr162440569824405993E08220987