rs9947276

Homo sapiens
A>T
ZNF407 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A==0337 (10071/29884,GnomAD)
A==0409 (11933/29118,TOPMED)
A==0321 (1608/5008,1000G)
A==0299 (1151/3854,ALSPAC)
A==0279 (1035/3708,TWINSUK)
chr18:74780733 (GRCh38.p7) (18q22.3)
AD
GWASdb2 | GWASCatalog
1   publication(s)
See rs on genome
22 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 18NC_000018.10:g.74780733A>T
GRCh37.p13 chr 18NC_000018.9:g.72492689A>T
ZNF407 RefSeqGeneNG_013216.1:g.154771A>T

Gene: ZNF407, zinc finger protein 407(plus strand)

Molecule type Change Amino acid[Codon] SO Term
ZNF407 transcript variant 2NM_001146189.1:c.N/AIntron Variant
ZNF407 transcript variant 3NM_001146190.1:c.N/AIntron Variant
ZNF407 transcript variant 1NM_017757.2:c.N/AIntron Variant
ZNF407 transcript variant X2XM_005266726.4:c.N/AIntron Variant
ZNF407 transcript variant X6XM_006722500.3:c.N/AIntron Variant
ZNF407 transcript variant X2XM_011526068.2:c.N/AIntron Variant
ZNF407 transcript variant X4XM_011526069.2:c.N/AIntron Variant
ZNF407 transcript variant X5XM_011526070.1:c.N/AIntron Variant
ZNF407 transcript variant X3XM_017025838.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.610T=0.390
1000GenomesAmericanSub694A=0.200T=0.800
1000GenomesEast AsianSub1008A=0.052T=0.948
1000GenomesEuropeSub1006A=0.289T=0.711
1000GenomesGlobalStudy-wide5008A=0.321T=0.679
1000GenomesSouth AsianSub978A=0.330T=0.670
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.299T=0.701
The Genome Aggregation DatabaseAfricanSub8694A=0.564T=0.436
The Genome Aggregation DatabaseAmericanSub836A=0.160T=0.840
The Genome Aggregation DatabaseEast AsianSub1618A=0.054T=0.946
The Genome Aggregation DatabaseEuropeSub18434A=0.265T=0.734
The Genome Aggregation DatabaseGlobalStudy-wide29884A=0.337T=0.663
The Genome Aggregation DatabaseOtherSub302A=0.170T=0.830
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.409T=0.590
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.279T=0.721
PMID Title Author Journal
24962325Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.Kapoor MDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs99472769E-06alcohol dependence (age at onset)24962325

eQTL of rs9947276 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs9947276 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr187250958272509739E06816893
chr187250883572509567E06916146
chr187250958272509739E06916893
chr187249227872492328E070-361
chr187249775072497820E0705061
chr187250843972508756E07015750
chr187250883572509567E07016146
chr187250958272509739E07016893
chr187250982072510344E07017131
chr187253957172539621E07046882
chr187254018072540243E07047491
chr187254029772540398E07047608
chr187250764372508030E08114954
chr187250831572508373E08115626
chr187250843972508756E08115750
chr187250883572509567E08116146
chr187250958272509739E08116893
chr187250764372508030E08214954
chr187250831572508373E08215626
chr187250843972508756E08215750
chr187250883572509567E08216146
chr187250958272509739E08216893