DegronMD

Uniprot ID: Q7Z5P9

Source protein: Mucin-19

Source gene: MUC19

Class: DEG_SPOP_SBC_1

Location: 2997:3001

E3 ligase: SPOP

DEGRON score: 0.7382

ASA_SCORE: 87.28

COIL: 0.7918

CONS_SCORE: 0.3085

DSS_SCORE: 0.5318

HELIX: 0.0438

FCONS_SCORE: 1

RIG_SCORE: 0.729

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.G2998E	DO229370	BTCA	ICGC	AKTTS	DEG_SPOP_SBC_1	0.7199
p.G3005V	DO234323	ESAD	ICGC	AKTTS	DEG_SPOP_SBC_1	0.2222
p.A2996V	DO234285	ESAD	ICGC	AKTTS	DEG_SPOP_SBC_1	0.3056
p.P2992L	DO228846	LICA	ICGC	AKTTS	DEG_SPOP_SBC_1	0.1944
p.G3001V	DO24307	LUAD	ICGC	AKTTS	DEG_SPOP_SBC_1	0.7532
p.G2988R	ACH-000219	Skin Cancer	CCLE	AKTTS	DEG_SPOP_SBC_1	0.0833

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q7Z5P9	Mucin-19	DEG_SPOP_SBC_1	2997:3001	AKTTS	SPOP	0.7382	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons