DegronMD

Uniprot ID: Q9UJP4

Source protein: Kelch-like protein 21

Source gene: KLHL21

Class: DEG_APCC_DBOX_1

Location: 420:428

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.5388

ASA_SCORE: 37.5667

COIL: 0.2419

CONS_SCORE: 0.7718

DSS_SCORE: 0.1181

HELIX: 0.0029

FCONS_SCORE: 1.2477

RIG_SCORE: 0.8427

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.A426D	DO229022	LICA	ICGC	CRGRLYAIG	DEG_APCC_DBOX_1	0.6682

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9UJP4	Kelch-like protein 21	DEG_APCC_DBOX_1	420:428	CRGRLYAIG	APC,CDC20,FZR1	0.5388	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons