DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
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Degron:
DQLPDCYSTTP
Uniprot ID:
O60516
Source protein:
Eukaryotic translation initiation factor 4E-binding protein 3
Source gene:
EIF4EBP3
Class:
CBL_PTK
Location:
14:24
E3 ligase:
CBL
DEGRON score:
0.997
ASA_SCORE:
58.2909
COIL:
0.7841
CONS_SCORE:
0.5074
DSS_SCORE:
0.4656
HELIX:
0.0865
FCONS_SCORE:
0.8946
RIG_SCORE:
0.7262
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with EIF4EBP3 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of DQLPDCYSTTP
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
O60516
Eukaryotic translation initiation factor 4E-binding protein 3
CBL_PTK
14:24
DQLPDCYSTTP
CBL
0.997
More...
