DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
DQLPDCYSTTP
Uniprot ID:
O60516
Source protein:
Eukaryotic translation initiation factor 4E-binding protein 3
Source gene:
EIF4EBP3
Class:
CBL_PTK
Location:
14:24
E3 ligase:
CBL
DEGRON score:
0.997
ASA_SCORE:
58.2909
COIL:
0.7841
CONS_SCORE:
0.5074
DSS_SCORE:
0.4656
HELIX:
0.0865
FCONS_SCORE:
0.8946
RIG_SCORE:
0.7262
Degron related mutations and impact score
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Drug responses associated with EIF4EBP3 mutations
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All proteins holding degron of DQLPDCYSTTP
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Uniprot ID
Source protein
Degron class
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Hit
E3 ligase
Degron score
Detail
O60516
Eukaryotic translation initiation factor 4E-binding protein 3
CBL_PTK
14:24
DQLPDCYSTTP
CBL
0.997
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