DegronMD

Uniprot ID: P18583

Source protein: Protein SON

Source gene: SON

Class: DEG_APCC_DBOX_1

Location: 2342:2350

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.8804

ASA_SCORE: 68.4111

COIL: 0.651

CONS_SCORE: 0.8046

DSS_SCORE: 0.4091

HELIX: 0.0983

FCONS_SCORE: 1.0196

RIG_SCORE: 0.7961

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.G2358V	TCGA-D3-A3C6	SKCM	TCGA	DRKGLVAVG	DEG_APCC_DBOX_1	0.1111

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
P18583	Protein SON	DEG_APCC_DBOX_1	2342:2350	DRKGLVAVG	APC,CDC20,FZR1	0.8804	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons