DegronMD

Uniprot ID: Q8NET4

Source protein: Retrotransposon Gag-like protein 9

Source gene: RTL9

Class: DEG_SCF_TRCP1_1

Location: 109:114

E3 ligase: BTRC

DEGRON score: 0.9043

ASA_SCORE: 78.8833

COIL: 0.889

CONS_SCORE: 0.3491

DSS_SCORE: 0.3056

HELIX: 0.0837

FCONS_SCORE: 1.0322

RIG_SCORE: 0.6647

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.M105I	SIDM02045	Colorectal Carcinoma	GDSC	DSGALS	DEG_SCF_TRCP1_1	0.2222
p.A107S	SIDM00741	Small Cell Lung Carcinoma	GDSC	DSGALS	DEG_SCF_TRCP1_1	0.2778
p.A107S	NCI-H1694	lung	COSMIC	DSGALS	DEG_SCF_TRCP1_1	0.2778

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q8NET4	Retrotransposon Gag-like protein 9	DEG_SCF_TRCP1_1	96:101	DSGALS	BTRC	0.9674	More...
Q8NET4	Retrotransposon Gag-like protein 9	DEG_SCF_TRCP1_1	109:114	DSGALS	BTRC	0.9043	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons