DegronMD

Uniprot ID: Q8N3J3

Source protein: Homologous recombination OB-fold protein

Source gene: HROB

Class: DEG_SCF_TRCP1_1

Location: 576:581

E3 ligase: BTRC

DEGRON score: 0.96

ASA_SCORE: 68.7

COIL: 0.89

CONS_SCORE: 0.35

DSS_SCORE: 0.4554

HELIX: 0.0672

FCONS_SCORE: 0.6968

RIG_SCORE: 0.6223

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.S574C	SIDM00320	Non-Small Cell Lung Carcinoma	GDSC	DSGDGS	DEG_SCF_TRCP1_1	0.2778
p.Y573C	SIDM00533	Pancreatic Carcinoma	GDSC	DSGDGS	DEG_SCF_TRCP1_1	0.25
p.K584E	SIDM00241	Breast Carcinoma	GDSC	DSGDGS	DEG_SCF_TRCP1_1	0.6944

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q8N3J3	Homologous recombination OB-fold protein	DEG_SCF_TRCP1_1	576:581	DSGDGS	BTRC	0.96	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons