DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
DSGFVS
Uniprot ID:
Q765P7
Source protein:
Protein MTSS 2
Source gene:
MTSS2
Class:
DEG_SCF_TRCP1_1
Location:
327:332
E3 ligase:
BTRC
DEGRON score:
0.9991
ASA_SCORE:
72.8833
COIL:
0.819
CONS_SCORE:
0.5959
DSS_SCORE:
0.4992
HELIX:
0.0553
FCONS_SCORE:
1.1308
RIG_SCORE:
0.6404
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with MTSS2 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of DSGFVS
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q765P7
Protein MTSS 2
DEG_SCF_TRCP1_1
327:332
DSGFVS
BTRC
0.9991
More...