DegronMD - Q765P7(MTSS2)

MTSS2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P265S	SIDM00683	Prostate Carcinoma	GDSC	PSSSS	DEG_SPOP_SBC_1	265:269	Mutation altering degron motif	0.6752
p.T349A	SIDM00216	Colorectal Carcinoma	GDSC	DATYSKPP	CBL_PTK	334:341	Mutation rewiring degron network	0.1111
p.A714T	SIDM00331	B-Lymphoblastic Leukemia	GDSC	LSATPTEE	DEG_SCF_FBW7_2	699:706	Mutation rewiring degron network	0.1111
p.T315A	SIDM00487	Colorectal Carcinoma	GDSC	PATTT	DEG_SPOP_SBC_1	313:317	Mutation altering degron motif	0.7139
p.S338F	SIDM00217	Colorectal Carcinoma	GDSC	DATYSKPP	CBL_PTK	334:341	Mutation altering degron motif	0.9093
p.S283G	SIDM01608	Endometrial Carcinoma	GDSC	APSSS	DEG_SPOP_SBC_1	278:282	Mutation blocking phosphorylation signal	0.75
p.R271Q	SIDM01619	Endometrial Carcinoma	GDSC	PSSSS	DEG_SPOP_SBC_1	265:269	Mutation rewiring degron network	0.2778
p.R271Q	SIDM01619	Endometrial Carcinoma	GDSC	APSSS	DEG_SPOP_SBC_1	278:282	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc