DegronMD

Uniprot ID: Q7Z5P9

Source protein: Mucin-19

Source gene: MUC19

Class: DEG_SCF_TRCP1_1

Location: 425:430

E3 ligase: BTRC

DEGRON score: 0.9612

ASA_SCORE: 57.7167

COIL: 0.7698

CONS_SCORE: 0.5019

DSS_SCORE: 0.6719

HELIX: 0.008

FCONS_SCORE: 0.8143

RIG_SCORE: 0.5424

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.L426R	DO234323	ESAD	ICGC	DSGGNT	DEG_SCF_TRCP1_1	0.8428
p.L426R	DO233248	GACA	ICGC	DSGGNT	DEG_SCF_TRCP1_1	0.8428
p.D428Y	DO218030	GACA	ICGC	DSGGNT	DEG_SCF_TRCP1_1	0.7325
p.K415N	DO220877	MELA	ICGC	DSGGNT	DEG_SCF_TRCP1_1	0.0556
p.P438Q	DO228567	PRAD	ICGC	DSGGNT	DEG_SCF_TRCP1_1	0.1111
p.D428E	ACH-000986	Colon/Colorectal Cancer	CCLE	DSGGNT	DEG_SCF_TRCP1_1	0.6758

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q7Z5P9	Mucin-19	DEG_SCF_TRCP1_1	425:430	DSGGNT	BTRC	0.9612	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons