DegronMD

Uniprot ID: Q8N5Q1

Source protein: Golgi associated RAB2 interactor protein 5B

Source gene: GARIN5B

Class: DEG_SCF_TRCP1_1

Location: 349:354

E3 ligase: BTRC

DEGRON score: 0.8761

ASA_SCORE: 70.2

COIL: 0.8728

CONS_SCORE: 0.5168

DSS_SCORE: 0.4947

HELIX: 0.0885

FCONS_SCORE: 0.9536

RIG_SCORE: 0.6486

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.G351R	DO231284	PACA	ICGC	DSGGST	DEG_SCF_TRCP1_1	0.7568
p.S356L	ACH-000670	Lung Cancer	CCLE	DSGGST	DEG_SCF_TRCP1_1	0.2778
p.G351V	ACH-000803	Lung Cancer	CCLE	DSGGST	DEG_SCF_TRCP1_1	0.7532

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q8N5Q1	Golgi associated RAB2 interactor protein 5B	DEG_SCF_TRCP1_1	349:354	DSGGST	BTRC	0.8761	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons