DegronMD

Uniprot ID: O75691

Source protein: Small subunit processome component 20 homolog

Source gene: UTP20

Class: DEG_SCF_TRCP1_1

Location: 1746:1751

E3 ligase: BTRC

DEGRON score: 0.9979

ASA_SCORE: 70.3333

COIL: 0.8365

CONS_SCORE: 0.2376

DSS_SCORE: 0.7242

HELIX: 0.1307

FCONS_SCORE: 1.0748

RIG_SCORE: 0.536

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.T1759K	TCGA-09-2044	OV	TCGA	DSGGTS	DEG_SCF_TRCP1_1	0.1111
p.T1759K	DO28923	OV	ICGC	DSGGTS	DEG_SCF_TRCP1_1	0.1111
p.K1753E	TCGA-43-8118	LUSC	TCGA	DSGGTS	DEG_SCF_TRCP1_1	0.2778
p.K1753E	DO45471	LUSC	ICGC	DSGGTS	DEG_SCF_TRCP1_1	0.2778
p.D1746Y	DO32896	PACA	ICGC	DSGGTS	DEG_SCF_TRCP1_1	0.7325

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
O75691	Small subunit processome component 20 homolog	DEG_SCF_TRCP1_1	1746:1751	DSGGTS	BTRC	0.9979	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons