DegronMD

Uniprot ID: Q9P2P6

Source protein: StAR-related lipid transfer protein 9

Source gene: STARD9

Class: DEG_SCF_TRCP1_1

Location: 311:317

E3 ligase: BTRC

DEGRON score: 0.9852

ASA_SCORE: 70.1286

COIL: 0.8436

CONS_SCORE: 0.4607

DSS_SCORE: 0.5695

HELIX: 0.0711

FCONS_SCORE: 0.8657

RIG_SCORE: 0.5904

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.T321I	TCGA-EC-A24G	UCEC	TCGA	DSGILSS	DEG_SCF_TRCP1_1	0.2222
p.T321I	DO40996	UCEC	ICGC	DSGILSS	DEG_SCF_TRCP1_1	0.2222
p.P318T	TCGA-EY-A547	UCEC	TCGA	DSGILSS	DEG_SCF_TRCP1_1	0.3056
p.P318T	DO48188	UCEC	ICGC	DSGILSS	DEG_SCF_TRCP1_1	0.3056
p.V306D	TCGA-FI-A2F4	UCEC	TCGA	DSGILSS	DEG_SCF_TRCP1_1	0.1944
p.V306D	DO43434	UCEC	ICGC	DSGILSS	DEG_SCF_TRCP1_1	0.1944
p.G309C	DO228952	LICA	ICGC	DSGILSS	DEG_SCF_TRCP1_1	0.2778
p.S322I	DO229045	LICA	ICGC	DSGILSS	DEG_SCF_TRCP1_1	0.6389
p.P318L	DO218912	SKCA	ICGC	DSGILSS	DEG_SCF_TRCP1_1	0.3056

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9P2P6	StAR-related lipid transfer protein 9	DEG_SCF_TRCP1_1	311:317	DSGILSS	BTRC	0.9852	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons