DegronMD

Uniprot ID: Q86XK3

Source protein: Swi5-dependent recombination DNA repair protein 1 homolog

Source gene: SFR1

Class: DEG_SCF_TRCP1_1

Location: 131:136

E3 ligase: BTRC

DEGRON score: 0.9064

ASA_SCORE: 74.4333

COIL: 0.8315

CONS_SCORE: 0.3491

DSS_SCORE: 0.2793

HELIX: 0.148

FCONS_SCORE: 1.0335

RIG_SCORE: 0.6862

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.A141T	DO219892	DLBC	ICGC	DSGSCS	DEG_SCF_TRCP1_1	0.1944
p.A141S	DO228978	LICA	ICGC	DSGSCS	DEG_SCF_TRCP1_1	0.1944
p.C122F	DO229031	LICA	ICGC	DSGSCS	DEG_SCF_TRCP1_1	0.0833
p.K145N	DO43186	UCEC	ICGC	DSGSCS	DEG_SCF_TRCP1_1	0.0833

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q86XK3	Swi5-dependent recombination DNA repair protein 1 homolog	DEG_SCF_TRCP1_1	131:136	DSGSCS	BTRC	0.9064	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons