DegronMD

Uniprot ID: Q9H2G2

Source protein: STE20-like serine/threonine-protein kinase

Source gene: SLK

Class: DEG_SCF_TRCP1_1

Location: 776:781

E3 ligase: BTRC

DEGRON score: 0.9511

ASA_SCORE: 80.5667

COIL: 0.7692

CONS_SCORE: 0.3039

DSS_SCORE: 0.4397

HELIX: 0.2035

FCONS_SCORE: 0.8845

RIG_SCORE: 0.6855

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.S779L	DO222662	MELA	ICGC	DSGSIS	DEG_SCF_TRCP1_1	0.7667
p.S779L	DO35442	PACA	ICGC	DSGSIS	DEG_SCF_TRCP1_1	0.7667
p.S779L	SIDM00330	Neuroblastoma	GDSC	DSGSIS	DEG_SCF_TRCP1_1	0.7667

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9H2G2	STE20-like serine/threonine-protein kinase	DEG_SCF_TRCP1_1	776:781	DSGSIS	BTRC	0.9511	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons