DegronMD

Uniprot ID: Q9ULW5

Source protein: Ras-related protein Rab-26

Source gene: RAB26

Class: DEG_SCF_TRCP1_1

Location: 71:77

E3 ligase: BTRC

DEGRON score: 0.5945

ASA_SCORE: 43.2571

COIL: 0.7163

CONS_SCORE: 0.9432

DSS_SCORE: 0.0208

HELIX: 0.0604

FCONS_SCORE: 1.3352

RIG_SCORE: 0.8611

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.R61C	DO219031	BLCA	ICGC	DSGVGKT	DEG_SCF_TRCP1_1	0.0556
p.L74V	DO49976	CESC	ICGC	DSGVGKT	DEG_SCF_TRCP1_1	0.6765
p.R69L	DO50841	LICA	ICGC	DSGVGKT	DEG_SCF_TRCP1_1	0.2778
p.R69L	DO26430	LUSC	ICGC	DSGVGKT	DEG_SCF_TRCP1_1	0.2778
p.R61S	DO37515	SKCM	ICGC	DSGVGKT	DEG_SCF_TRCP1_1	0.0556
p.H65N	DO37491	SKCM	ICGC	DSGVGKT	DEG_SCF_TRCP1_1	0.2778
p.T64I	DO41020	UCEC	ICGC	DSGVGKT	DEG_SCF_TRCP1_1	0.1389

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9ULW5	Ras-related protein Rab-26	DEG_SCF_TRCP1_1	71:77	DSGVGKT	BTRC	0.5945	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons