DegronMD

Uniprot ID: Q6PGQ7

Source protein: Protein aurora borealis

Source gene: BORA

Class: DEG_SCF_TRCP1_1

Location: 496:501

E3 ligase: BTRC

DEGRON score: 0.9758

ASA_SCORE: 56.9667

COIL: 0.6975

CONS_SCORE: 0.5472

DSS_SCORE: 0.3629

HELIX: 0.1138

FCONS_SCORE: 1.1332

RIG_SCORE: 0.7122

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.D510N	TCGA-4Z-AA87	BLCA	TCGA	DSGYNT	DEG_SCF_TRCP1_1	0.0833
p.D510N	DO218990	BLCA	ICGC	DSGYNT	DEG_SCF_TRCP1_1	0.0833
p.I493T	DO231566	LINC	ICGC	DSGYNT	DEG_SCF_TRCP1_1	0.25
p.M495I	DO218894	SKCA	ICGC	DSGYNT	DEG_SCF_TRCP1_1	0.3056

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q6PGQ7	Protein aurora borealis	DEG_SCF_TRCP1_1	496:501	DSGYNT	BTRC	0.9758	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons