DegronMD

Uniprot ID: Q9Y3M8

Source protein: StAR-related lipid transfer protein 13

Source gene: STARD13

Class: DEG_COP1_1

Location: 884:892

E3 ligase: COP1

DEGRON score: 0.6159

ASA_SCORE: 71.9

COIL: 0.7221

CONS_SCORE: 0.437

DSS_SCORE: 0.2971

HELIX: 0.2133

FCONS_SCORE: 1.0859

RIG_SCORE: 0.8168

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.V883M	TCGA-AN-A0FS	BRCA	TCGA	EAEIHVPTL	DEG_COP1_1	0.3056
p.S881L	TCGA-CG-4306	STAD	TCGA	EAEIHVPTL	DEG_COP1_1	0.25
p.R879H	TCGA-CM-4751	COAD	TCGA	EAEIHVPTL	DEG_COP1_1	0.1944
p.L895F	TCGA-D3-A1QA	SKCM	TCGA	EAEIHVPTL	DEG_COP1_1	0.25
p.L895V	TCGA-EY-A1GI	UCEC	TCGA	EAEIHVPTL	DEG_COP1_1	0.25
p.A876G	TCGA-R6-A6L6	ESCA	TCGA	EAEIHVPTL	DEG_COP1_1	0.1111
p.E900K	TCGA-WE-AAA0	SKCM	TCGA	EAEIHVPTL	DEG_COP1_1	0.1111
p.R879G	TCGA-ZC-AAA7	THYM	TCGA	EAEIHVPTL	DEG_COP1_1	0.1944
p.T902A	DO8490	COAD	ICGC	EAEIHVPTL	DEG_COP1_1	0.0556
p.Q880L	DO219922	DLBC	ICGC	EAEIHVPTL	DEG_COP1_1	0.2222
p.L883R	DO233888	GACA	ICGC	EAEIHVPTL	DEG_COP1_1	0.3056
p.A887D	DO229028	LICA	ICGC	EAEIHVPTL	DEG_COP1_1	0.7793
p.T876K	DO229031	LICA	ICGC	EAEIHVPTL	DEG_COP1_1	0.1111
p.T876I	DO23681	LUAD	ICGC	EAEIHVPTL	DEG_COP1_1	0.1111
p.M886I	DO51171	PAEN	ICGC	EAEIHVPTL	DEG_COP1_1	0.7618
p.H889N	DO37405	SKCM	ICGC	EAEIHVPTL	DEG_COP1_1	0.7423
p.H889N	DO37971	SKCM	ICGC	EAEIHVPTL	DEG_COP1_1	0.7423
p.V889M	SIDM00967	Ovarian Carcinoma	GDSC	EAEIHVPTL	DEG_COP1_1	0.7208
p.E884G	ACH-001274	Sarcoma	CCLE	EAEIHVPTL	DEG_COP1_1	0.7199
p.G895V	NCI-H2141	lung	COSMIC	EAEIHVPTL	DEG_COP1_1	0.25

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9Y3M8	StAR-related lipid transfer protein 13	DEG_COP1_1	884:892	EAEIHVPTL	COP1	0.6159	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons