DegronMD

Uniprot ID: Q09666

Source protein: Neuroblast differentiation-associated protein AHNAK

Source gene: AHNAK

Class: DEG_COP1_1

Location: 1798:1806

E3 ligase: COP1

DEGRON score: 0.9899

ASA_SCORE: 71.3222

COIL: 0.7362

CONS_SCORE: 0.183

DSS_SCORE: 0.5056

HELIX: 0.0306

FCONS_SCORE: 0.9832

RIG_SCORE: 0.7326

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.A1801V	TCGA-A5-A0G2	UCEC	TCGA	EIDASVPEL	DEG_COP1_1	0.5825
p.A1801V	DO41235	UCEC	ICGC	EIDASVPEL	DEG_COP1_1	0.5825
p.P1813L	DO233254	GACA	ICGC	EIDASVPEL	DEG_COP1_1	0.1389
p.A1801D	DO229027	LICA	ICGC	EIDASVPEL	DEG_COP1_1	0.6682
p.R1811K	DO220902	MELA	ICGC	EIDASVPEL	DEG_COP1_1	0.1944

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q09666	Neuroblast differentiation-associated protein AHNAK	DEG_COP1_1	1798:1806	EIDASVPEL	COP1	0.9899	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons