DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
EREILSPLF
Uniprot ID:
Q5VWN6
Source protein:
Protein TASOR 2
Source gene:
TASOR2
Class:
DEG_APCC_DBOX_1
Location:
670:678
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.9754
ASA_SCORE:
99.3778
COIL:
0.8073
CONS_SCORE:
0.4945
DSS_SCORE:
0.5447
HELIX:
0.1303
FCONS_SCORE:
0.8505
RIG_SCORE:
0.7548
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with TASOR2 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of EREILSPLF
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q5VWN6
Protein TASOR 2
DEG_APCC_DBOX_1
670:678
EREILSPLF
APC,CDC20,FZR1
0.9754
More...