DegronMD

Uniprot ID: Q8TCU4

Source protein: Alstrom syndrome protein 1

Source gene: ALMS1

Class: DEG_APCC_DBOX_1

Location: 102:110

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.7642

ASA_SCORE: 96.2667

COIL: 0.7356

CONS_SCORE: 0.3372

DSS_SCORE: 0.3391

HELIX: 0.0587

FCONS_SCORE: 0.6988

RIG_SCORE: 0.7508

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.I109S	DO23288	LINC	ICGC	ERTSLEKIV	DEG_APCC_DBOX_1	0.7341
p.P111S	DO222843	MELA	ICGC	ERTSLEKIV	DEG_APCC_DBOX_1	0.3056
p.E119K	DO41020	UCEC	ICGC	ERTSLEKIV	DEG_APCC_DBOX_1	0.0833

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q8TCU4	Alstrom syndrome protein 1	DEG_APCC_DBOX_1	102:110	ERTSLEKIV	APC,CDC20,FZR1	0.7642	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons