DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
FDLHSE
Uniprot ID:
Q69YN4
Source protein:
Protein virilizer homolog
Source gene:
VIRMA
Class:
LIG_APCC_ABBA_1
Location:
1563:1568
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.5041
ASA_SCORE:
49.3333
COIL:
0.3248
CONS_SCORE:
0.5142
DSS_SCORE:
0.2599
HELIX:
0.654
FCONS_SCORE:
1.0124
RIG_SCORE:
0.8021
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with VIRMA mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of FDLHSE
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q69YN4
Protein virilizer homolog
LIG_APCC_ABBA_1
1563:1568
FDLHSE
APC,CDC20,FZR1
0.5041
More...