DegronMD

Uniprot ID: Q9P2P6

Source protein: StAR-related lipid transfer protein 9

Source gene: STARD9

Class: LIG_APCC_ABBA_1

Location: 1281:1286

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.7918

ASA_SCORE: 77.8833

COIL: 0.7132

CONS_SCORE: 0.318

DSS_SCORE: 0.1812

HELIX: 0.2053

FCONS_SCORE: 1.131

RIG_SCORE: 0.7144

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.E1286D	SIDM01124	Non-Small Cell Lung Carcinoma	GDSC	FQPHCE	LIG_APCC_ABBA_1	0.5647
p.E1286D	ACH-000945	Lung Cancer	CCLE	FQPHCE	LIG_APCC_ABBA_1	0.5647
p.P1295L	SIDM00863	Burkitt's Lymphoma	GDSC	FQPHCE	LIG_APCC_ABBA_1	0.0833

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9P2P6	StAR-related lipid transfer protein 9	LIG_APCC_ABBA_1	1281:1286	FQPHCE	APC,CDC20,FZR1	0.7918	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons