DegronMD

Uniprot ID: Q6ZV80

Source protein: Putative uncharacterized protein LINC02898

Source gene: LINC02898

Class: DEG_APCC_DBOX_1

Location: 60:68

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.5691

ASA_SCORE: 65.2333

COIL: 0.6777

CONS_SCORE: 1

DSS_SCORE: 0.6321

HELIX: 0.1636

FCONS_SCORE: 1

RIG_SCORE: 0.6526

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.N69K	DO229035	LICA	ICGC	GRHTLSQVP	DEG_APCC_DBOX_1	0.3056
p.P68L	DO220906	MELA	ICGC	GRHTLSQVP	DEG_APCC_DBOX_1	0.6471
p.R59G	DO229208	THCA	ICGC	GRHTLSQVP	DEG_APCC_DBOX_1	0.3056
p.P54S	SIDM00375	Head and Neck Carcinoma	GDSC	GRHTLSQVP	DEG_APCC_DBOX_1	0.1667

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q6ZV80	Putative uncharacterized protein LINC02898	DEG_APCC_DBOX_1	60:68	GRHTLSQVP	APC,CDC20,FZR1	0.5691	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons