DegronMD

Uniprot ID: Q9C0C6

Source protein: CLOCK-interacting pacemaker

Source gene: CIPC

Class: DEG_ODPH_VHL_1

Location: 163:174

E3 ligase: VHL

DEGRON score: 0.9993

ASA_SCORE: 72.7667

COIL: 0.8524

CONS_SCORE: 0.6797

DSS_SCORE: 0.5627

HELIX: 0.0266

FCONS_SCORE: 1.2642

RIG_SCORE: 0.6541

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.A164V	TCGA-A5-A1OF	UCEC	TCGA	IAPHPGKRGLSL	DEG_ODPH_VHL_1	0.6936
p.R170M	TCGA-AX-A1CE	UCEC	TCGA	IAPHPGKRGLSL	DEG_ODPH_VHL_1	0.7521
p.R170M	TCGA-DF-A2KU	UCEC	TCGA	IAPHPGKRGLSL	DEG_ODPH_VHL_1	0.7521

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9C0C6	CLOCK-interacting pacemaker	DEG_ODPH_VHL_1	163:174	IAPHPGKRGLSL	VHL	0.9993	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons