DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
CPH
CGC
Degron:
IAPPSFDGTTMSF
Uniprot ID:
D6RIA3
Source protein:
Uncharacterized protein C4orf54
Source gene:
C4orf54
Class:
DEG_ODPH_VHL_1
Location:
1776:1788
E3 ligase:
VHL
DEGRON score:
0.8201
ASA_SCORE:
56.6385
COIL:
0.6119
CONS_SCORE:
0.4624
DSS_SCORE:
0.4574
HELIX:
0.0335
FCONS_SCORE:
0.8134
RIG_SCORE:
0.7258
Degron related mutations and impact score
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Drug responses associated with C4orf54 mutations
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All proteins holding degron of IAPPSFDGTTMSF
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Uniprot ID
Source protein
Degron class
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Hit
E3 ligase
Degron score
Detail
D6RIA3
Uncharacterized protein C4orf54
DEG_ODPH_VHL_1
1776:1788
IAPPSFDGTTMSF
VHL
0.8201
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