DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
CPH
CGC
Degron:
IAPPSFDGTTMSF
Uniprot ID:
D6RIA3
Source protein:
Uncharacterized protein C4orf54
Source gene:
C4orf54
Class:
DEG_ODPH_VHL_1
Location:
1776:1788
E3 ligase:
VHL
DEGRON score:
0.8201
ASA_SCORE:
56.6385
COIL:
0.6119
CONS_SCORE:
0.4624
DSS_SCORE:
0.4574
HELIX:
0.0335
FCONS_SCORE:
0.8134
RIG_SCORE:
0.7258
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with C4orf54 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of IAPPSFDGTTMSF
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
D6RIA3
Uncharacterized protein C4orf54
DEG_ODPH_VHL_1
1776:1788
IAPPSFDGTTMSF
VHL
0.8201
More...